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X Demographics
Mendeley readers
Attention Score in Context
| Title |
A role for inflammatory metabolites as modulators of the glutamate N-methyl-d-aspartate receptor in depression and suicidality
|
|---|---|
| Published in |
Brain, Behavior & Immunity, August 2014
|
| DOI | 10.1016/j.bbi.2014.07.012 |
| Pubmed ID | |
| Authors |
Cecilie Bay-Richter, Klas R. Linderholm, Chai K. Lim, Martin Samuelsson, Lil Träskman-Bendz, Gilles J. Guillemin, Sophie Erhardt, Lena Brundin |
| Abstract |
Patients with depression and suicidality suffer from low-grade neuroinflammation. Pro-inflammatory cytokines activate indoleamine 2,3-dioxygenase, an initial enzyme of the kynurenine pathway. This pathway produces neuroactive metabolites, including quinolinic- and kynurenic acid, binding to the glutamate N-methyl-d-aspartate-receptor, which is hypothesized to be part of the neural mechanisms underlying symptoms of depression. We therefore hypothesized that symptoms of depression and suicidality would fluctuate over time in patients prone to suicidal behavior, depending on the degree of inflammation and kynurenine metabolite levels in the cerebrospinal fluid (CSF). |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 33% |
| Sweden | 1 | 33% |
| Unknown | 1 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 217 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 5 | 2% |
| Poland | 1 | <1% |
| Canada | 1 | <1% |
| Unknown | 210 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 34 | 16% |
| Student > Master | 28 | 13% |
| Student > Bachelor | 26 | 12% |
| Researcher | 25 | 12% |
| Student > Doctoral Student | 17 | 8% |
| Other | 35 | 16% |
| Unknown | 52 | 24% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 45 | 21% |
| Neuroscience | 40 | 18% |
| Psychology | 22 | 10% |
| Agricultural and Biological Sciences | 19 | 9% |
| Biochemistry, Genetics and Molecular Biology | 14 | 6% |
| Other | 16 | 7% |
| Unknown | 61 | 28% |
Attention Score in Context
This research output has an Altmetric Attention Score of 17. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 December 2022.
All research outputs
#2,111,620
of 25,374,917 outputs
Outputs from Brain, Behavior & Immunity
#629
of 3,454 outputs
Outputs of similar age
#20,909
of 243,234 outputs
Outputs of similar age from Brain, Behavior & Immunity
#7
of 49 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,454 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 21.9. This one has done well, scoring higher than 81% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 243,234 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 91% of its contemporaries.
We're also able to compare this research output to 49 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 85% of its contemporaries.