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K13-Propeller Polymorphisms in Plasmodium falciparum Parasites From Sub-Saharan Africa

Overview of attention for article published in Journal of Infectious Diseases, November 2014
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  • Good Attention Score compared to outputs of the same age (68th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (55th percentile)

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6 X users

Citations

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226 Dimensions

Readers on

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287 Mendeley
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2 CiteULike
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Title
K13-Propeller Polymorphisms in Plasmodium falciparum Parasites From Sub-Saharan Africa
Published in
Journal of Infectious Diseases, November 2014
DOI 10.1093/infdis/jiu608
Pubmed ID
Authors

Edwin Kamau, Susana Campino, Lucas Amenga-Etego, Eleanor Drury, Deus Ishengoma, Kimberly Johnson, Dieudonne Mumba, Mihir Kekre, William Yavo, Daniel Mead, Marielle Bouyou-Akotet, Tobias Apinjoh, Lemu Golassa, Milijaona Randrianarivelojosia, Ben Andagalu, Oumou Maiga-Ascofare, Alfred Amambua-Ngwa, Paulina Tindana, Anita Ghansah, Bronwyn MacInnis, Dominic Kwiatkowski, Abdoulaye A. Djimde

Abstract

Mutations in the Plasmodium falciparum K13-propeller domain have recently been shown to be important determinants of artemisinin resistance in South-East Asia (SEA). This study investigated the prevalence of K13-propeller polymorphisms across sub-Saharan Africa. 1212 P. falciparum samples collected from twelve countries were sequenced. None of the K13-propeller mutations previously reported in SEA were found, but 22 unique mutations were detected, of which seven were non-synonymous. Allele frequencies ranged between 1-3%. Three mutations were observed in more than one country, and the A578S was present in parasites from five countries. This study provides baseline prevalence of K13-propeller mutations in sub-Saharan Africa.

X Demographics

X Demographics

The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 287 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 4 1%
Burkina Faso 1 <1%
Ethiopia 1 <1%
Tanzania, United Republic of 1 <1%
Vietnam 1 <1%
United States 1 <1%
Unknown 278 97%

Demographic breakdown

Readers by professional status Count As %
Student > Master 57 20%
Student > Ph. D. Student 54 19%
Researcher 52 18%
Student > Bachelor 22 8%
Student > Doctoral Student 12 4%
Other 44 15%
Unknown 46 16%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 78 27%
Agricultural and Biological Sciences 77 27%
Medicine and Dentistry 38 13%
Immunology and Microbiology 15 5%
Pharmacology, Toxicology and Pharmaceutical Science 6 2%
Other 21 7%
Unknown 52 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 July 2017.
All research outputs
#8,201,370
of 25,411,814 outputs
Outputs from Journal of Infectious Diseases
#6,936
of 14,806 outputs
Outputs of similar age
#87,086
of 274,768 outputs
Outputs of similar age from Journal of Infectious Diseases
#78
of 181 outputs
Altmetric has tracked 25,411,814 research outputs across all sources so far. This one has received more attention than most of these and is in the 67th percentile.
So far Altmetric has tracked 14,806 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 16.4. This one has gotten more attention than average, scoring higher than 52% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 274,768 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 68% of its contemporaries.
We're also able to compare this research output to 181 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 55% of its contemporaries.