| Title |
RETRACTED ARTICLE:l-glutamine supplementation induces insulin resistance in adipose tissue and improves insulin signalling in liver and muscle of rats with diet-induced obesity
|
|---|---|
| Published in |
Diabetologia, June 2007
|
| DOI | 10.1007/s00125-007-0723-z |
| Pubmed ID | |
| Authors |
P. O. Prada, S. M. Hirabara, C. T. de Souza, A. A. Schenka, H. G. Zecchin, J. Vassallo, L. A. Velloso, E. Carneiro, J. B. C. Carvalheira, R. Curi, M. J. Saad |
| Abstract |
Diet-induced obesity (DIO) is associated with insulin resistance in liver and muscle, but not in adipose tissue. Mice with fat-specific disruption of the gene encoding the insulin receptor are protected against DIO and glucose intolerance. In cell culture, glutamine induces insulin resistance in adipocytes, but has no effect in muscle cells. We investigated whether supplementation of a high-fat diet with glutamine induces insulin resistance in adipose tissue in the rat, improving insulin sensitivity in the whole animal. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 63 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 1 | 2% |
| India | 1 | 2% |
| Australia | 1 | 2% |
| Unknown | 60 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 11 | 17% |
| Student > Master | 10 | 16% |
| Professor > Associate Professor | 9 | 14% |
| Student > Bachelor | 6 | 10% |
| Professor | 6 | 10% |
| Other | 11 | 17% |
| Unknown | 10 | 16% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 21 | 33% |
| Medicine and Dentistry | 12 | 19% |
| Biochemistry, Genetics and Molecular Biology | 8 | 13% |
| Engineering | 3 | 5% |
| Immunology and Microbiology | 2 | 3% |
| Other | 8 | 13% |
| Unknown | 9 | 14% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 September 2018.
All research outputs
#14,789,079
of 22,769,322 outputs
Outputs from Diabetologia
#4,380
of 5,034 outputs
Outputs of similar age
#58,713
of 68,360 outputs
Outputs of similar age from Diabetologia
#22
of 25 outputs
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We're also able to compare this research output to 25 others from the same source and published within six weeks on either side of this one. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.