| Title |
Connectivity-Based Parcellation of the Amygdala Predicts Social Skills in Adolescents with Autism Spectrum Disorder
|
|---|---|
| Published in |
Journal of Autism and Developmental Disorders, November 2017
|
| DOI | 10.1007/s10803-017-3370-3 |
| Pubmed ID | |
| Authors |
Annika Rausch, Wei Zhang, Christian F. Beckmann, Jan K. Buitelaar, Wouter B. Groen, Koen V. Haak |
| Abstract |
Amygdala dysfunction plays a role in the social impairments in autism spectrum disorders (ASD), but it is unclear which of its subregions are abnormal in ASD. This study compared the volume and functional connectivity (FC) strength of three FC-defined amygdala subregions between ASD and controls, and assessed their relation to social skills in ASD. A subregion associated with the social perception network was enlarged in ASD (F1 = 7.842, p = .008) and its volume correlated significantly with symptom severity (social skills: r = .548, p = .009). Posthoc analysis revealed that the enlargement was driven by the vmPFC amygdala network. These findings refine our understanding of abnormal amygdala connectivity in ASD and may inform future strategies for therapeutic interventions targeting the amygdalofrontal pathway. |
X Demographics
The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 3 | 50% |
| Germany | 1 | 17% |
| Portugal | 1 | 17% |
| Unknown | 1 | 17% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 67% |
| Scientists | 1 | 17% |
| Practitioners (doctors, other healthcare professionals) | 1 | 17% |
Mendeley readers
The data shown below were compiled from readership statistics for 96 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 96 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 15 | 16% |
| Researcher | 15 | 16% |
| Student > Bachelor | 14 | 15% |
| Student > Doctoral Student | 8 | 8% |
| Student > Master | 8 | 8% |
| Other | 11 | 11% |
| Unknown | 25 | 26% |
| Readers by discipline | Count | As % |
|---|---|---|
| Psychology | 22 | 23% |
| Neuroscience | 16 | 17% |
| Nursing and Health Professions | 7 | 7% |
| Computer Science | 5 | 5% |
| Social Sciences | 4 | 4% |
| Other | 6 | 6% |
| Unknown | 36 | 38% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 April 2019.
All research outputs
#13,442,783
of 23,867,274 outputs
Outputs from Journal of Autism and Developmental Disorders
#3,247
of 5,240 outputs
Outputs of similar age
#156,322
of 334,826 outputs
Outputs of similar age from Journal of Autism and Developmental Disorders
#74
of 122 outputs
Altmetric has tracked 23,867,274 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 5,240 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.2. This one is in the 37th percentile – i.e., 37% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 334,826 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 52% of its contemporaries.
We're also able to compare this research output to 122 others from the same source and published within six weeks on either side of this one. This one is in the 39th percentile – i.e., 39% of its contemporaries scored the same or lower than it.