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Longitudinal change of COPD assessment test (CAT) in a telehealthcare cohort is associated with exacerbation risk

Overview of attention for article published in International Journal of Chronic Obstructive Pulmonary Disease, October 2017
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Title
Longitudinal change of COPD assessment test (CAT) in a telehealthcare cohort is associated with exacerbation risk
Published in
International Journal of Chronic Obstructive Pulmonary Disease, October 2017
DOI 10.2147/copd.s141646
Pubmed ID
Authors

Frank Rassouli, Florent Baty, Daiana Stolz, Werner Christian Albrich, Michael Tamm, Sandra Widmer, Martin Hugo Brutsche

Abstract

There are only scarce data regarding the evolution of the chronic obstructive pulmonary disease (COPD) assessment test (CAT) over time. Our aim was to investigate the evolution of the CAT in a telehealthcare (THC) cohort and to evaluate its potential to predict exacerbations. The CAT was measured weekly over up to 1 year in 40 COPD patients undergoing a THC intervention. The evolution of the CAT was analyzed using linear regression. The association between this evolution and the occurrence of exacerbations was evaluated using the Andersen-Gill formulation of the Cox proportional hazards model for the analysis of recurrent time-to-event data with time-varying predictors. The median CAT at inclusion was 17 (interquartile range 13-22) points. During the study, 25% of patients had a significant negative slope (median -7 points per year [ppy]), 38% were stable (median +0 ppy) and 38% had a significant positive slope (median +6 ppy). The median slope of the CAT in the overall cohort was +1 (interquartile range -3 to +6) ppy. A significant positive association was found between the change in CAT scores and the risk of exacerbations (hazard ratio =1.08, 95% CI: 1.03-1.13; p<0.001). There was an 8% increase of the risk of exacerbation per unit increase in CAT. We detected a significant learning effect in filling out the CAT in 18.4% of patients with a median learning phase of five filled questionnaires. Sixty-three percent of the COPD patients monitored by THC experienced a stable or improved CAT during 1-year follow-up. We found a significant positive association between the evolution of the CAT over time and the risk of exacerbations. In about one-fifth of patients, there was a significant learning effect in filling out the CAT, before reliable results could be obtained. The evolution of the CAT could help to assess the risk for future exacerbations.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 63 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 63 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 9 14%
Student > Bachelor 9 14%
Other 8 13%
Student > Doctoral Student 7 11%
Student > Ph. D. Student 7 11%
Other 6 10%
Unknown 17 27%
Readers by discipline Count As %
Medicine and Dentistry 13 21%
Nursing and Health Professions 11 17%
Psychology 4 6%
Computer Science 3 5%
Business, Management and Accounting 2 3%
Other 11 17%
Unknown 19 30%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 November 2017.
All research outputs
#22,764,772
of 25,382,440 outputs
Outputs from International Journal of Chronic Obstructive Pulmonary Disease
#2,404
of 2,578 outputs
Outputs of similar age
#291,092
of 331,218 outputs
Outputs of similar age from International Journal of Chronic Obstructive Pulmonary Disease
#63
of 70 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,578 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.5. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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We're also able to compare this research output to 70 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.