| Title |
Clinical Significance of Endothelial Dysfunction in Essential Hypertension
|
|---|---|
| Published in |
Current Hypertension Reports, September 2015
|
| DOI | 10.1007/s11906-015-0596-3 |
| Pubmed ID | |
| Authors |
Eugenia Gkaliagkousi, Eleni Gavriilaki, Areti Triantafyllou, Stella Douma |
| Abstract |
The endothelium is recognized as a major determinant of vascular physiology and pathophysiology. Over the last few decades, a plethora of studies have implicated endothelial dysfunction in the progression of atherosclerosis and the subclinical target organ damage observed in essential hypertension. However, the clinical significance of diagnosing endothelial dysfunction in patients with essential hypertension remains under investigation. Although a number of vascular and non-vascular markers of endothelial dysfunction have been proposed, there is an ongoing quest for a marker in the clinical setting that is optimal, inexpensive, and reproducible. In addition, endothelial dysfunction emerges as a promising therapeutic target of agents that are readily available in clinical practice. In this context, a better understanding of its role in essential hypertension becomes of great importance. Here, we aim to investigate the clinical significance of endothelial dysfunction in essential hypertension by accumulating novel data on (a) early diagnosis using robust markers with prognostic value in cardiovascular risk prediction, (b) the association of endothelial dysfunction with subclinical vascular organ damage, and |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 109 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 1 | <1% |
| Chile | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 106 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 16 | 15% |
| Student > Doctoral Student | 13 | 12% |
| Student > Bachelor | 12 | 11% |
| Researcher | 9 | 8% |
| Student > Ph. D. Student | 9 | 8% |
| Other | 23 | 21% |
| Unknown | 27 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 37 | 34% |
| Agricultural and Biological Sciences | 10 | 9% |
| Biochemistry, Genetics and Molecular Biology | 9 | 8% |
| Nursing and Health Professions | 9 | 8% |
| Pharmacology, Toxicology and Pharmaceutical Science | 5 | 5% |
| Other | 11 | 10% |
| Unknown | 28 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 November 2017.
All research outputs
#18,576,001
of 23,007,887 outputs
Outputs from Current Hypertension Reports
#553
of 734 outputs
Outputs of similar age
#194,135
of 269,068 outputs
Outputs of similar age from Current Hypertension Reports
#12
of 14 outputs
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