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Data Monitoring in Clinical Trials

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Cover of 'Data Monitoring in Clinical Trials'

Table of Contents

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    Book Overview
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    Chapter 1 Monitoring Committees: Why and How
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    Chapter 2 Lessons Learned
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    Chapter 3 FDA and Clinical Trial Data Monitoring Committees
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    Chapter 4 Introduction to Case Studies Showing Benefit from the Intervention
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    Chapter 5 Assessing Possible Late Treatment Effects Early: The Diabetic Retinopathy Study Experience
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    Chapter 6 Data and Safety Monitoring in the Beta-Blocker Heart Attack Trial: Early Experience in Formal Monitoring Methods
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    Chapter 7 Data Monitoring for the Aspirin Component of the Physicians’ Health Study: Issues in Early Termination for a Major Secondary Endpoint
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    Chapter 8 Early Termination of the Stroke Prevention in Atrial Fibrillation I Trial: Protecting Participant Interests in the Face of Scientific Uncertainties and the Cruel Play of Chance
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    Chapter 9 Early Termination of the Diabetes Control and Complications Trial
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    Chapter 10 Data Monitoring in the AIDS Clinical Trials Group Study #981: Conflicting Interim Results
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    Chapter 11 Challenges in Monitoring the Breast Cancer Prevention Trial
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    Chapter 12 Data Monitoring Experience in the Metoprolol CR/XL Randomized Intervention Trial in Chronic Heart Failure: Potentially High-Risk Treatment in High-Risk Patients
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    Chapter 13 Stopping the Randomized Aldactone Evaluation Study Early for Efficacy
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    Chapter 14 Data Monitoring in the Heart Outcomes Prevention Evaluation and the Clopidogrel in Unstable Angina to Prevent Recurrent Ischemic Events Trials: Avoiding Important Information Loss
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    Chapter 15 The Data Monitoring Experience in the Candesartan in Heart Failure Assessment of Reduction in Mortality and Morbidity Program
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    Chapter 16 Introduction to Case Studies Showing Harmful Effects of the Intervention
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    Chapter 17 Breaking New Ground: Data Monitoring in the Coronary Drug Project
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    Chapter 18 The Data Monitoring Experience in the Cardiac Arrhythmia Suppression Trial: The Need to Be Prepared Early
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    Chapter 19 Data Monitoring in the Prospective Randomized Milrinone Survival Evaluation: Dealing With an Agonizing Trend
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    Chapter 20 Stopping the Carotene and Retinol Efficacy Trial: The Viewpoint of the Safety and Endpoint Monitoring Committee
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    Chapter 21 Monitoring a Clinical Trial With Waiver of Informed Consent: Diaspirin Cross-Linked Hemoglobin for Emergency Treatment of Post—Traumatic Shock
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    Chapter 22 Consideration of Early Stopping and Other Challenges in Monitoring the Heart and Estrogen/Progestin Replacement Study
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    Chapter 23 Data Monitoring in the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial: Early Termination of the Doxazosin Treatment Arm
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    Chapter 24 Case 19: Data Monitoring Experience in the Moxonidine Congestive Heart Failure Trial
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    Chapter 25 Data Monitoring of a Placebo-Controlled Trial of Daclizumab in Acute Graft-Versus-Host Disease
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    Chapter 26 Introduction to Case Studies With Special Issues
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    Chapter 27 Clinical Trials of Herpes Simplex Encephalitis: The Role of the Data Monitoring Committee
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    Chapter 28 The Nocturnal Oxygen Therapy Trial Data Monitoring Experience: Problem With Reporting Lags
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    Chapter 29 Stopping a Trial for Futility: The Cooperative New Scandinavian Enalapril Survival Study II
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    Chapter 30 Lessons From Warfarin Trials in Atrial Fibrillation: Missing the Window of Opportunity
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    Chapter 31 Data Monitoring Experience in the AIDS Toxoplasmic Encephalitis Study
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    Chapter 32 Data Monitoring in the Randomized Evaluation of Strategies for Left Ventricular Dysfunction Pilot Study: When Reasonable People Disagree
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    Chapter 33 The Data Monitoring Experience in the Carvedilol Post-Infarct Survival Control in Left Ventricular Dysfunction Study: Hazards of Changing Primary Outcomes
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    Chapter 34 Data Monitoring in Clinical Trials
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    Chapter 35 Making Independence Work: Monitoring the Bevacizumab Colorectal Cancer Clinical Trial
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Title
Data Monitoring in Clinical Trials
Published by
Springer US, January 2006
DOI 10.1007/0-387-30107-0
ISBNs
978-0-387-20330-0, 978-0-387-30107-5
Editors

DeMets, David L., Furberg, Curt D., Friedman, Lawrence M., DeMets, David L., Furberg, Curt D., Friedman, Lawrence M.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 26 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 4%
Colombia 1 4%
Germany 1 4%
Unknown 23 88%

Demographic breakdown

Readers by professional status Count As %
Researcher 6 23%
Student > Master 4 15%
Student > Ph. D. Student 4 15%
Professor > Associate Professor 3 12%
Other 2 8%
Other 3 12%
Unknown 4 15%
Readers by discipline Count As %
Medicine and Dentistry 6 23%
Social Sciences 4 15%
Computer Science 3 12%
Mathematics 3 12%
Agricultural and Biological Sciences 2 8%
Other 4 15%
Unknown 4 15%