Title |
A collaborative study of the etiology of breast cancer subtypes in African American women: the AMBER consortium
|
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Published in |
Cancer Causes & Control, December 2013
|
DOI | 10.1007/s10552-013-0332-8 |
Pubmed ID | |
Authors |
Julie R. Palmer, Christine B. Ambrosone, Andrew F. Olshan |
Abstract |
Breast cancer is a heterogeneous disease, with at least five intrinsic subtypes defined by molecular characteristics. Tumors that express the estrogen receptor (ER+) have better outcomes than ER- tumors, due in part to the success of hormonal therapies that target ER+ tumors. The incidence of ER- breast cancer, and the subset of ER- cancers that are basal-like, is about twice as high among African American (AA) women as among US women of European descent (EA). This disparity appears to explain, in part, the disproportionately high mortality from breast cancer that occurs in AA women. Epidemiologic research on breast cancer in AA women lags behind research in EA women. Here, we review differences in the etiology of breast cancer subtypes among AA women and describe a new consortium of ongoing studies of breast cancer in AA women. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
India | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 2% |
Unknown | 52 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 13 | 25% |
Researcher | 9 | 17% |
Student > Master | 7 | 13% |
Student > Bachelor | 5 | 9% |
Student > Doctoral Student | 3 | 6% |
Other | 9 | 17% |
Unknown | 7 | 13% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 17 | 32% |
Agricultural and Biological Sciences | 10 | 19% |
Biochemistry, Genetics and Molecular Biology | 5 | 9% |
Nursing and Health Professions | 4 | 8% |
Arts and Humanities | 2 | 4% |
Other | 5 | 9% |
Unknown | 10 | 19% |