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Patient-reported factors associated with adherence to adjuvant endocrine therapy after breast cancer: an integrative review

Overview of attention for article published in Breast Cancer Research and Treatment, November 2017
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Title
Patient-reported factors associated with adherence to adjuvant endocrine therapy after breast cancer: an integrative review
Published in
Breast Cancer Research and Treatment, November 2017
DOI 10.1007/s10549-017-4561-5
Pubmed ID
Authors

Leah K. Lambert, Lynda G. Balneaves, A. Fuchsia Howard, Carolyn C. Gotay

Abstract

Adjuvant endocrine therapy (AET) significantly reduces recurrence and mortality in women with breast cancer (BrCa). Despite the efficacy of AET in improving BrCa outcomes, up to 50% of women do not adhere to prescribed AET regimens. While numerous demographic and clinical predictors influence adherence and persistence, few studies have identified the patient-reported factors that influence AET adherence and persistence. The aim was to examine the patient-reported personal, social, and structural factors influencing BrCa survivors' adherence and persistence with AET. An integrative review was undertaken wherein PubMed, Medline, CINAHL, Embase, and PsycINFO databases were searched using keyword descriptors and database subject headings. Inclusion criteria included quantitative or qualitative peer-reviewed studies written in English that assessed AET adherence and/or persistence through objective measurement or self-report and included patient-reported factors found to influence adherence and/or persistence. The data extracted from eligible studies were entered into a matrix, and systematically compared and iteratively analyzed using relational autonomy as an organizing theoretical framework. A total of 43 manuscripts (9 qualitative and 34 quantitative) were reviewed. Several personal, social, and structural factors were identified that influenced AET adherence and persistence, including side effects, necessity beliefs, self-efficacy, the patient-healthcare provider relationship, social support, and continuity of follow-up care. An increasing number of studies have focused on identifying the patient-reported factors that influence AET adherence and persistence. This review highlights important personal, social, and structural factors that act as facilitators and barriers in adhering to and persisting with long-term AET. Acknowledging and addressing these factors is key to providing women with the care needed to improve suboptimal adherence and persistence.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 103 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 103 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 16 16%
Student > Master 13 13%
Researcher 9 9%
Student > Bachelor 9 9%
Student > Doctoral Student 8 8%
Other 12 12%
Unknown 36 35%
Readers by discipline Count As %
Medicine and Dentistry 18 17%
Psychology 15 15%
Nursing and Health Professions 12 12%
Pharmacology, Toxicology and Pharmaceutical Science 5 5%
Business, Management and Accounting 3 3%
Other 13 13%
Unknown 37 36%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 November 2017.
All research outputs
#14,830,566
of 23,007,887 outputs
Outputs from Breast Cancer Research and Treatment
#3,192
of 4,681 outputs
Outputs of similar age
#193,620
of 330,783 outputs
Outputs of similar age from Breast Cancer Research and Treatment
#41
of 62 outputs
Altmetric has tracked 23,007,887 research outputs across all sources so far. This one is in the 34th percentile – i.e., 34% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,681 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.2. This one is in the 31st percentile – i.e., 31% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 330,783 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 62 others from the same source and published within six weeks on either side of this one. This one is in the 33rd percentile – i.e., 33% of its contemporaries scored the same or lower than it.