Title |
Depression, Coronary Artery Disease, and Physical Activity: How Much Exercise Is Enough?
|
---|---|
Published in |
Clinical Therapeutics, November 2014
|
DOI | 10.1016/j.clinthera.2014.10.003 |
Pubmed ID | |
Authors |
Janey C. Peterson, Mary E. Charlson, Martin T. Wells, Margaret Altemus |
Abstract |
The mechanisms by which depressive symptoms negatively affect clinical outcomes in patients with coronary artery disease (CAD) remain poorly understood. Previous interventions that have attempted to treat depressive symptoms in patients with CAD to improve their clinical outcomes have been disappointing. Our objectives were, among a cohort of CAD patients, to evaluate the impact of depressive symptoms over time, controlling for comorbidity, in determining both successful long-term lifestyle change (ie, increased physical activity), and cardiovascular morbidity and mortality outcomes. In addition, we examined the impact of physical activity changes over time on 2 known mediators of cardiovascular morbidity: parasympathetic tone and inflammation. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 3 | 19% |
United Kingdom | 2 | 13% |
Spain | 1 | 6% |
Canada | 1 | 6% |
India | 1 | 6% |
Unknown | 8 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 13 | 81% |
Scientists | 2 | 13% |
Science communicators (journalists, bloggers, editors) | 1 | 6% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Mexico | 1 | <1% |
Luxembourg | 1 | <1% |
Brazil | 1 | <1% |
Unknown | 233 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 41 | 17% |
Student > Bachelor | 36 | 15% |
Student > Ph. D. Student | 34 | 14% |
Researcher | 17 | 7% |
Student > Doctoral Student | 17 | 7% |
Other | 39 | 17% |
Unknown | 52 | 22% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 54 | 23% |
Psychology | 39 | 17% |
Nursing and Health Professions | 27 | 11% |
Sports and Recreations | 25 | 11% |
Neuroscience | 6 | 3% |
Other | 28 | 12% |
Unknown | 57 | 24% |