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Solar elastosis and cutaneous melanoma: A site‐specific analysis

Overview of attention for article published in International Journal of Cancer, November 2014
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Title
Solar elastosis and cutaneous melanoma: A site‐specific analysis
Published in
International Journal of Cancer, November 2014
DOI 10.1002/ijc.29335
Pubmed ID
Authors

Marina Kvaskoff, Nirmala Pandeya, Adèle C. Green, Susan Perry, Catherine Baxter, Marcia B. Davis, Rohan Mortimore, Lorraine Westacott, Dominic Wood, Joe Triscott, Richard Williamson, David C. Whiteman

Abstract

Cutaneous melanomas are postulated to arise through at least two causal pathways, namely the "chronic sun exposure" and "nevus" pathways. While chronic sun exposure probably causes many head/neck melanomas, its role at other sites is unclear. In a population-based, case-case comparison study conducted in Brisbane, Australia, we determined the prevalence and epidemiologic correlates of chronic solar damage in skin adjacent to invasive, incident melanomas on the trunk (n = 418) or head/neck (n = 92) among patients aged 18-79 in 2007-2010. Participants self-reported information about environmental and phenotypic factors, and a dermatologist counted nevi and actinic keratoses. Dermatopathologists assessed solar elastosis adjacent to each melanoma using a four-point scale (nil, mild, moderate, marked), and noted the presence or absence of adjacent neval remnants. We measured associations between various factors and solar elastosis using polytomous logistic regression. Marked or moderate solar elastosis was observed in 10% and 27%, respectively, of trunk melanomas, and 60% and 17%, respectively, of head/neck melanomas. At both sites, marked elastosis was positively associated with age (ptrend  < 0.0001) and inversely associated with neval remnants (ptrend  < 0.001). For trunk melanomas, marked elastosis was associated with highest quartiles of total sun exposure [odds-ratio (OR) = 5.47, 95% confidence interval (CI) = 1.08-27.60] and facial freckling (OR = 2.98, 95% CI = 1.17-7.56), and inversely associated with deeply tanning skin (OR = 0.29, 95% CI = 0.08-1.11) and high nevus counts (OR = 0.08, 95% CI = 0.01-0.66). Mostly similar associations were observed with moderate solar elastosis. About one in three trunk melanomas in Queensland have evidence of moderate-to-marked sun damage, and they differ in risk associations from those without.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 36 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 36 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 6 17%
Student > Ph. D. Student 5 14%
Student > Bachelor 3 8%
Other 3 8%
Student > Postgraduate 2 6%
Other 6 17%
Unknown 11 31%
Readers by discipline Count As %
Medicine and Dentistry 13 36%
Biochemistry, Genetics and Molecular Biology 5 14%
Agricultural and Biological Sciences 2 6%
Engineering 2 6%
Economics, Econometrics and Finance 1 3%
Other 1 3%
Unknown 12 33%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 November 2014.
All research outputs
#19,955,316
of 24,525,936 outputs
Outputs from International Journal of Cancer
#10,755
of 12,085 outputs
Outputs of similar age
#273,997
of 372,165 outputs
Outputs of similar age from International Journal of Cancer
#87
of 108 outputs
Altmetric has tracked 24,525,936 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 12,085 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.8. This one is in the 5th percentile – i.e., 5% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 372,165 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 14th percentile – i.e., 14% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 108 others from the same source and published within six weeks on either side of this one. This one is in the 11th percentile – i.e., 11% of its contemporaries scored the same or lower than it.