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Mendeley readers
Attention Score in Context
| Title |
Spider venomics: implications for drug discovery
|
|---|---|
| Published in |
Future Medicinal Chemistry, October 2014
|
| DOI | 10.4155/fmc.14.103 |
| Pubmed ID | |
| Authors |
Sandy S Pineda, Eivind AB Undheim, Darshani B Rupasinghe, Maria P Ikonomopoulou, Glenn F King |
| Abstract |
Over a period of more than 300 million years, spiders have evolved complex venoms containing an extraordinary array of toxins for prey capture and defense against predators. The major components of most spider venoms are small disulfide-bridged peptides that are highly stable and resistant to proteolytic degradation. Moreover, many of these peptides have high specificity and potency toward molecular targets of therapeutic importance. This unique combination of bioactivity and stability has made spider-venom peptides valuable both as pharmacological tools and as leads for drug development. This review describes recent advances in spider-venom-based drug discovery pipelines. We discuss spider-venom-derived peptides that are currently under investigation for treatment of a diverse range of pathologies including pain, stroke and cancer. |
Mendeley readers
The data shown below were compiled from readership statistics for 51 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| India | 1 | 2% |
| Unknown | 50 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 10 | 20% |
| Student > Ph. D. Student | 8 | 16% |
| Student > Bachelor | 7 | 14% |
| Researcher | 7 | 14% |
| Professor > Associate Professor | 4 | 8% |
| Other | 8 | 16% |
| Unknown | 7 | 14% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 16 | 31% |
| Agricultural and Biological Sciences | 10 | 20% |
| Pharmacology, Toxicology and Pharmaceutical Science | 5 | 10% |
| Chemistry | 4 | 8% |
| Environmental Science | 2 | 4% |
| Other | 6 | 12% |
| Unknown | 8 | 16% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 November 2014.
All research outputs
#22,778,370
of 25,393,528 outputs
Outputs from Future Medicinal Chemistry
#1,051
of 1,195 outputs
Outputs of similar age
#227,169
of 265,694 outputs
Outputs of similar age from Future Medicinal Chemistry
#34
of 34 outputs
Altmetric has tracked 25,393,528 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,195 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.8. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 265,694 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 34 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.