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Evaluation of nicotine and cotinine analogs as potential neuroprotective agents for Alzheimer’s disease

Overview of attention for article published in Bioorganic & Medicinal Chemistry Letters, February 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (84th percentile)
  • High Attention Score compared to outputs of the same age and source (81st percentile)

Mentioned by

news
1 news outlet

Citations

dimensions_citation
47 Dimensions

Readers on

mendeley
44 Mendeley
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Title
Evaluation of nicotine and cotinine analogs as potential neuroprotective agents for Alzheimer’s disease
Published in
Bioorganic & Medicinal Chemistry Letters, February 2014
DOI 10.1016/j.bmcl.2014.02.008
Pubmed ID
Authors

Jie Gao, Bao-Ling Adam, Alvin V. Terry

Abstract

The currently available therapies for Alzheimer's disease (AD) and related forms of dementia are limited by modest efficacy, adverse side effects, and the fact that they do not prevent the relentless progression of the illness. The purpose of the studies described here was to investigate the neuroprotective effects of the nicotine metabolite cotinine as well as a small series of cotinine and nicotine analogs (including stereoisomers) and to compare their effects to the four clinically prescribed AD therapies.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 44 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Australia 1 2%
Brazil 1 2%
Unknown 42 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 20%
Student > Master 6 14%
Student > Bachelor 5 11%
Student > Postgraduate 3 7%
Professor > Associate Professor 3 7%
Other 9 20%
Unknown 9 20%
Readers by discipline Count As %
Chemistry 13 30%
Pharmacology, Toxicology and Pharmaceutical Science 3 7%
Medicine and Dentistry 3 7%
Psychology 3 7%
Neuroscience 2 5%
Other 11 25%
Unknown 9 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 November 2014.
All research outputs
#4,369,647
of 25,374,647 outputs
Outputs from Bioorganic & Medicinal Chemistry Letters
#2,159
of 13,778 outputs
Outputs of similar age
#50,592
of 330,518 outputs
Outputs of similar age from Bioorganic & Medicinal Chemistry Letters
#19
of 110 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. Compared to these this one has done well and is in the 82nd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 13,778 research outputs from this source. They receive a mean Attention Score of 4.9. This one has done well, scoring higher than 84% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 330,518 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 84% of its contemporaries.
We're also able to compare this research output to 110 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 81% of its contemporaries.