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Next-Generation Sequencing in Clinical Oncology: Next Steps Towards Clinical Validation

Overview of attention for article published in Cancers, November 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (87th percentile)
  • High Attention Score compared to outputs of the same age and source (84th percentile)

Mentioned by

twitter
11 X users
patent
1 patent
facebook
1 Facebook page
googleplus
1 Google+ user

Citations

dimensions_citation
46 Dimensions

Readers on

mendeley
124 Mendeley
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Title
Next-Generation Sequencing in Clinical Oncology: Next Steps Towards Clinical Validation
Published in
Cancers, November 2014
DOI 10.3390/cancers6042296
Pubmed ID
Authors

Nigel C. Bennett, Camile S. Farah

Abstract

Compelling evidence supports the transition of next generation sequencing (NGS) technology from a research environment into clinical practice. Before NGS technologies are fully adopted in the clinic, they should be thoroughly scrutinised for their potential as powerful diagnostic and prognostic tools. The importance placed on generating accurate NGS data, and consequently appropriate clinical interpretation, has stimulated much international discussion regarding the creation and implementation of strict guidelines and regulations for NGS clinical use. In the context of clinical oncology, NGS technologies are currently transitioning from a clinical research background into a setting where they will contribute significantly to individual patient cancer management. This paper explores the steps that have been taken, and those still required, for the transition of NGS into the clinical area, with particular emphasis placed on validation in the setting of clinical oncology.

X Demographics

X Demographics

The data shown below were collected from the profiles of 11 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 124 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 4 3%
Netherlands 1 <1%
Italy 1 <1%
Canada 1 <1%
United Kingdom 1 <1%
China 1 <1%
Denmark 1 <1%
Unknown 114 92%

Demographic breakdown

Readers by professional status Count As %
Researcher 29 23%
Student > Ph. D. Student 19 15%
Other 18 15%
Student > Master 16 13%
Student > Postgraduate 8 6%
Other 19 15%
Unknown 15 12%
Readers by discipline Count As %
Agricultural and Biological Sciences 32 26%
Biochemistry, Genetics and Molecular Biology 28 23%
Medicine and Dentistry 27 22%
Computer Science 6 5%
Engineering 2 2%
Other 10 8%
Unknown 19 15%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 May 2020.
All research outputs
#3,385,457
of 24,532,617 outputs
Outputs from Cancers
#1,280
of 14,595 outputs
Outputs of similar age
#47,232
of 372,854 outputs
Outputs of similar age from Cancers
#3
of 13 outputs
Altmetric has tracked 24,532,617 research outputs across all sources so far. Compared to these this one has done well and is in the 86th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 14,595 research outputs from this source. They receive a mean Attention Score of 4.9. This one has done particularly well, scoring higher than 91% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 372,854 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 87% of its contemporaries.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 84% of its contemporaries.