| Title |
Evaluation of pupillary response to light in patients with glaucoma: a study using computerized pupillometry
|
|---|---|
| Published in |
International Ophthalmology, February 2014
|
| DOI | 10.1007/s10792-014-9920-1 |
| Pubmed ID | |
| Authors |
Alessio Martucci, Massimo Cesareo, Domenico Napoli, Roberto Pietro Sorge, Federico Ricci, Raffaele Mancino, Carlo Nucci |
| Abstract |
The aim of this study was to evaluate pupillary response to light stimulation in patients with different stages of glaucoma using computerized pupillometry. We conducted a retrospective study on a group of 44 glaucoma patients who had undergone complete ophthalmological examination, visual field test (Humphrey SITA Standard 24-2) and monocular dynamic pupillometry (MonCV3 Metrovision). Eyes were classified into stages of glaucoma according to visual field damage using the Glaucoma Staging System 2. A group of 18 healthy subjects, homogeneous for age and sex with glaucoma patients, was used as a control. The following parameters were considered-latency and duration of contraction and dilatation; initial, minimum, maximum, and mean pupil diameter; amplitude of contraction; contraction and dilatation speed; and percent pupil contraction (PPC). PPC and pupil contraction speed and minimum diameter showed covariate correlation with the stages of glaucoma. The control group significantly differed from the stage 3 group in terms of PPC and from the stage 4 group in terms of minimum diameter. There were significant differences between the stage 5 group and stage 1, 2, 3 and control groups. Ordinal logistic regression showed a correlation between pupil contraction speed, minimum diameter, PPC, initial diameter and the stage of glaucoma. The study showed that glaucoma damage is associated with altered values of pupillary response to light. This event may be the consequence of the progressive loss of retinal ganglion cells and their axons induced by glaucoma. |
X Demographics
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Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 47 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Turkey | 1 | 2% |
| United States | 1 | 2% |
| Germany | 1 | 2% |
| Unknown | 44 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 7 | 15% |
| Student > Ph. D. Student | 6 | 13% |
| Student > Bachelor | 4 | 9% |
| Researcher | 3 | 6% |
| Student > Doctoral Student | 2 | 4% |
| Other | 8 | 17% |
| Unknown | 17 | 36% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 17 | 36% |
| Engineering | 3 | 6% |
| Neuroscience | 3 | 6% |
| Computer Science | 3 | 6% |
| Nursing and Health Professions | 2 | 4% |
| Other | 3 | 6% |
| Unknown | 16 | 34% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 November 2014.
All research outputs
#20,243,777
of 22,771,140 outputs
Outputs from International Ophthalmology
#658
of 1,032 outputs
Outputs of similar age
#192,939
of 224,167 outputs
Outputs of similar age from International Ophthalmology
#10
of 27 outputs
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