| Title |
Impact of Access Site Practice on Clinical Outcomes in Patients Undergoing Percutaneous Coronary Intervention Following Thrombolysis for ST-Segment Elevation Myocardial Infarction in the United Kingdom An Insight From the British Cardiovascular Intervention Society Dataset
|
|---|---|
| Published in |
JACC: Cardiovascular Interventions, November 2017
|
| DOI | 10.1016/j.jcin.2017.07.049 |
| Pubmed ID | |
| Authors |
Muhammad Rashid, Claire A. Rushton, Chun Shing Kwok, Tim Kinnaird, Evangelos Kontopantelis, Ivan Olier, Peter Ludman, Mark A. De Belder, James Nolan, Mamas A. Mamas |
| Abstract |
This study sought to examine the relationship between access site practice and clinical outcomes in patients requiring percutaneous coronary intervention (PCI) following thrombolysis for ST-segment elevation myocardial infarction (STEMI). Transradial access (TRA) is associated with better outcomes in patients requiring PCI for STEMI. A significant proportion of STEMI patients may receive thrombolysis before undergoing PCI in many countries across the world. There are limited data around access site practice and its associated outcomes in this cohort of patients. The author used the British Cardiovascular Intervention Society dataset to investigate the outcomes of patients undergoing PCI following thrombolysis between 2007 and 2014. Patients were divided into TRA and transfemoral access groups depending on the access site used. Multiple logistic regression and propensity score matching were used to study the association of access site with in-hospital and long-term mortality, major bleeding, and access site-related complications. A total of 10,209 patients received thrombolysis and PCI during the study time. TRA was used in 48% (n = 4,959) of patients; 3.3% (n = 336) patients died in hospital, 1.6% (n = 165) of patients experienced major bleeding, 4.2% (n = 437) experienced major adverse cardiac events (MACE), and 4.6% (n = 468) experienced 30-day mortality. After multivariate adjustment, TRA was associated with significantly reduced odds of in-hospital mortality (odds ratio [OR]: 0.59; 95% confidence interval [CI]: 0.42 to 0.83; p = 0.002), major bleeding (OR: 0.45; 95% CI: 0.31 to 0.66; p < 0.001), MACE (OR: 0.72; 95% CI: 0.55 to 0.94; p = 0.01), and 30-day mortality (OR: 0.72; 95% CI: 0.55 to 0.94; p = 0.01). TRA is associated with decreased odds of bleeding complications, mortality, and MACE in patients undergoing PCI following thrombolysis and should be preferred access site choice in this cohort of patients. |
X Demographics
The data shown below were collected from the profiles of 41 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 14 | 34% |
| United Kingdom | 6 | 15% |
| Argentina | 3 | 7% |
| Canada | 2 | 5% |
| India | 1 | 2% |
| Australia | 1 | 2% |
| Saudi Arabia | 1 | 2% |
| Spain | 1 | 2% |
| Netherlands | 1 | 2% |
| Other | 0 | 0% |
| Unknown | 11 | 27% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 19 | 46% |
| Scientists | 12 | 29% |
| Practitioners (doctors, other healthcare professionals) | 7 | 17% |
| Science communicators (journalists, bloggers, editors) | 3 | 7% |
Mendeley readers
The data shown below were compiled from readership statistics for 48 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 48 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Other | 5 | 10% |
| Lecturer | 5 | 10% |
| Researcher | 5 | 10% |
| Student > Postgraduate | 4 | 8% |
| Student > Master | 3 | 6% |
| Other | 8 | 17% |
| Unknown | 18 | 38% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 21 | 44% |
| Nursing and Health Professions | 2 | 4% |
| Engineering | 2 | 4% |
| Social Sciences | 2 | 4% |
| Veterinary Science and Veterinary Medicine | 1 | 2% |
| Other | 0 | 0% |
| Unknown | 20 | 42% |
Attention Score in Context
This research output has an Altmetric Attention Score of 39. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 December 2017.
All research outputs
#1,053,856
of 25,382,440 outputs
Outputs from JACC: Cardiovascular Interventions
#399
of 4,032 outputs
Outputs of similar age
#22,034
of 340,752 outputs
Outputs of similar age from JACC: Cardiovascular Interventions
#11
of 93 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,032 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.2. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 340,752 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 93% of its contemporaries.
We're also able to compare this research output to 93 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 88% of its contemporaries.