| Title |
Brain and Gut Interactions in Irritable Bowel Syndrome: New Paradigms and New Understandings
|
|---|---|
| Published in |
Current Gastroenterology Reports, March 2014
|
| DOI | 10.1007/s11894-014-0379-z |
| Pubmed ID | |
| Authors |
Enrique Coss-Adame, Satish S. C. Rao |
| Abstract |
Irritable bowel syndrome (IBS) is characterized by abdominal pain and altered bowel habits. Visceral hypersensitivity is believed to be a key underlying mechanism that causes pain. There is evidence that interactions within the brain and gut axis (BGA), that involves both the afferent-ascending and the efferent-descending pathways, as well as the somatosensory cortex, insula, amygdala, anterior cingulate cortex, and hippocampus, are deranged in IBS showing both the activation and inactivation. Clinical manifestations of IBS such as pain, altered gut motility, and psychological dysfunction may each be explained, in part, through the changes in the BGA, but there is conflicting information, and its precise role is not fully understood. A better understanding of the BGA may shed more knowledge regarding the pathophysiology of IBS that in turn may lead to the discovery of novel therapies for this common disorder. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 158 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 1 | <1% |
| Unknown | 157 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 36 | 23% |
| Researcher | 18 | 11% |
| Student > Ph. D. Student | 17 | 11% |
| Student > Master | 17 | 11% |
| Student > Doctoral Student | 13 | 8% |
| Other | 32 | 20% |
| Unknown | 25 | 16% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 49 | 31% |
| Agricultural and Biological Sciences | 16 | 10% |
| Neuroscience | 15 | 9% |
| Nursing and Health Professions | 13 | 8% |
| Psychology | 7 | 4% |
| Other | 20 | 13% |
| Unknown | 38 | 24% |
Attention Score in Context
This research output has an Altmetric Attention Score of 19. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 October 2023.
All research outputs
#1,945,870
of 25,457,858 outputs
Outputs from Current Gastroenterology Reports
#3
of 3 outputs
Outputs of similar age
#19,259
of 236,041 outputs
Outputs of similar age from Current Gastroenterology Reports
#2
of 7 outputs
Altmetric has tracked 25,457,858 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 25.9. This one scored the same or higher as 0 of them.
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We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one. This one has scored higher than 5 of them.