| Title |
Estrogen receptor (ER) α mutations in breast cancer: hidden in plain sight
|
|---|---|
| Published in |
Breast Cancer Research and Treatment, February 2014
|
| DOI | 10.1007/s10549-014-2847-4 |
| Pubmed ID | |
| Authors |
Suzanne A. W. Fuqua, Guowei Gu, Yassine Rechoum |
| Abstract |
The idea that somatic ERα mutations could play an important role in the evolution of hormone-dependent breast cancers was proposed some years ago (Fuqua J Mammary Gland Biol Neoplasia 6(4):407-417, 2001; Dasgupta et al. Annu Rev Med 65:279-292, 2013), but has remained controversial until recently. A significant amount of new data has confirmed these initial observations and shown their significance, along with much additional work relevant to the treatment of breast cancer. Thus, it is the purpose of this review to summarize the research to date on the existence and clinical consequences of ERα mutations in primary and metastatic breast cancer. |
Mendeley readers
The data shown below were compiled from readership statistics for 64 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 1 | 2% |
| Unknown | 63 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 16 | 25% |
| Student > Bachelor | 9 | 14% |
| Student > Master | 8 | 13% |
| Researcher | 7 | 11% |
| Professor > Associate Professor | 4 | 6% |
| Other | 7 | 11% |
| Unknown | 13 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 15 | 23% |
| Medicine and Dentistry | 12 | 19% |
| Agricultural and Biological Sciences | 12 | 19% |
| Chemistry | 4 | 6% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 5% |
| Other | 5 | 8% |
| Unknown | 13 | 20% |
Attention Score in Context
This research output has an Altmetric Attention Score of 20. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 September 2021.
All research outputs
#1,548,177
of 22,771,140 outputs
Outputs from Breast Cancer Research and Treatment
#199
of 4,652 outputs
Outputs of similar age
#19,276
of 307,350 outputs
Outputs of similar age from Breast Cancer Research and Treatment
#4
of 50 outputs
Altmetric has tracked 22,771,140 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,652 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.2. This one has done particularly well, scoring higher than 95% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 307,350 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 93% of its contemporaries.
We're also able to compare this research output to 50 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 92% of its contemporaries.