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X Demographics
Mendeley readers
Attention Score in Context
| Title |
An organic fluorophore-nanodiamond hybrid sensor for photostable imaging and orthogonal, on-demand biosensing
|
|---|---|
| Published in |
Scientific Reports, November 2017
|
| DOI | 10.1038/s41598-017-15772-0 |
| Pubmed ID | |
| Authors |
Malcolm S. Purdey, Patrick K. Capon, Benjamin J. Pullen, Philipp Reineck, Nisha Schwarz, Peter J. Psaltis, Stephen J. Nicholls, Brant C. Gibson, Andrew D. Abell |
| Abstract |
Organic fluorescent probes are widely used to detect key biomolecules; however, they often lack the photostability required for extended intracellular imaging. Here we report a new hybrid nanomaterial (peroxynanosensor, PNS), consisting of an organic fluorescent probe bound to a nanodiamond, that overcomes this limitation to allow concurrent and extended cell-based imaging of the nanodiamond and ratiometric detection of hydrogen peroxide. Far-red fluorescence of the nanodiamond offers continuous monitoring without photobleaching, while the green fluorescence of the organic fluorescent probe attached to the nanodiamond surface detects hydrogen peroxide on demand. PNS detects basal production of hydrogen peroxide within M1 polarised macrophages and does not affect macrophage growth during prolonged co-incubation. This nanosensor can be used for extended bio-imaging not previously possible with an organic fluorescent probe, and is spectrally compatible with both Hoechst 33342 and MitoTracker Orange stains for hyperspectral imaging. |
X Demographics
The data shown below were collected from the profiles of 17 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Australia | 7 | 41% |
| Switzerland | 1 | 6% |
| Belgium | 1 | 6% |
| Unknown | 8 | 47% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 12 | 71% |
| Scientists | 4 | 24% |
| Science communicators (journalists, bloggers, editors) | 1 | 6% |
Mendeley readers
The data shown below were compiled from readership statistics for 31 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 31 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 10 | 32% |
| Researcher | 5 | 16% |
| Student > Master | 5 | 16% |
| Professor | 1 | 3% |
| Other | 1 | 3% |
| Other | 1 | 3% |
| Unknown | 8 | 26% |
| Readers by discipline | Count | As % |
|---|---|---|
| Physics and Astronomy | 7 | 23% |
| Agricultural and Biological Sciences | 4 | 13% |
| Biochemistry, Genetics and Molecular Biology | 3 | 10% |
| Chemistry | 2 | 6% |
| Materials Science | 2 | 6% |
| Other | 2 | 6% |
| Unknown | 11 | 35% |
Attention Score in Context
This research output has an Altmetric Attention Score of 13. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 December 2017.
All research outputs
#2,432,596
of 23,393,513 outputs
Outputs from Scientific Reports
#21,285
of 126,437 outputs
Outputs of similar age
#55,830
of 440,023 outputs
Outputs of similar age from Scientific Reports
#639
of 4,022 outputs
Altmetric has tracked 23,393,513 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 126,437 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 18.3. This one has done well, scoring higher than 83% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 440,023 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 87% of its contemporaries.
We're also able to compare this research output to 4,022 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 84% of its contemporaries.