| Title |
Breast cancer adaptive resistance: HER2 and cancer stem cell repopulation in a heterogeneous tumor society
|
|---|---|
| Published in |
Journal of Cancer Research and Clinical Oncology, August 2013
|
| DOI | 10.1007/s00432-013-1494-1 |
| Pubmed ID | |
| Authors |
Nadire Duru, Demet Candas, Guochun Jiang, Jian Jian Li |
| Abstract |
The lethal effects of cancer are associated with the enhanced tumor aggressiveness in recurrent and metastatic lesions that show resistant phenotype to anti-cancer therapy, a major barrier to improving overall survival of cancer patients. The presence of heterogeneous populations of cancer cells within a specific tumor including the tumor-initiating cells or so-called cancer stem cells (CSCs) has linked the acquired resistance (AR, or adaptive resistance). Herein, we discuss the CSC-mediated tumor repopulation in AR of breast cancer in this review. |
Mendeley readers
The data shown below were compiled from readership statistics for 74 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Netherlands | 1 | 1% |
| United States | 1 | 1% |
| Unknown | 72 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 17 | 23% |
| Student > Ph. D. Student | 12 | 16% |
| Student > Master | 8 | 11% |
| Student > Bachelor | 8 | 11% |
| Professor | 3 | 4% |
| Other | 11 | 15% |
| Unknown | 15 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 18 | 24% |
| Biochemistry, Genetics and Molecular Biology | 14 | 19% |
| Agricultural and Biological Sciences | 13 | 18% |
| Engineering | 2 | 3% |
| Chemistry | 2 | 3% |
| Other | 7 | 9% |
| Unknown | 18 | 24% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 July 2023.
All research outputs
#7,601,772
of 23,815,455 outputs
Outputs from Journal of Cancer Research and Clinical Oncology
#570
of 2,632 outputs
Outputs of similar age
#65,029
of 201,340 outputs
Outputs of similar age from Journal of Cancer Research and Clinical Oncology
#6
of 14 outputs
Altmetric has tracked 23,815,455 research outputs across all sources so far. This one has received more attention than most of these and is in the 67th percentile.
So far Altmetric has tracked 2,632 research outputs from this source. They receive a mean Attention Score of 3.6. This one has done well, scoring higher than 77% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 201,340 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.
We're also able to compare this research output to 14 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 57% of its contemporaries.