| Title |
Ongoing Developments in Sporadic Inclusion Body Myositis
|
|---|---|
| Published in |
Current Rheumatology Reports, November 2014
|
| DOI | 10.1007/s11926-014-0477-9 |
| Pubmed ID | |
| Authors |
Pedro M. Machado, Mhoriam Ahmed, Stefen Brady, Qiang Gang, Estelle Healy, Jasper M. Morrow, Amanda C. Wallace, Liz Dewar, Gita Ramdharry, Matthew Parton, Janice L. Holton, Henry Houlden, Linda Greensmith, Michael G. Hanna |
| Abstract |
Sporadic inclusion body myositis (IBM) is an acquired muscle disorder associated with ageing, for which there is no effective treatment. Ongoing developments include: genetic studies that may provide insights regarding the pathogenesis of IBM, improved histopathological markers, the description of a new IBM autoantibody, scrutiny of the diagnostic utility of clinical features and biomarkers, the refinement of diagnostic criteria, the emerging use of MRI as a diagnostic and monitoring tool, and new pathogenic insights that have led to novel therapeutic approaches being trialled for IBM, including treatments with the objective of restoring protein homeostasis and myostatin blockers. The effect of exercise in IBM continues to be investigated. However, despite these ongoing developments, the aetiopathogenesis of IBM remains uncertain. A translational and multidisciplinary collaborative approach is critical to improve the diagnosis, treatment, and care of patients with IBM. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 67% |
| United Kingdom | 1 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 67% |
| Practitioners (doctors, other healthcare professionals) | 1 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 65 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 2% |
| Spain | 1 | 2% |
| Unknown | 63 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 14 | 22% |
| Student > Ph. D. Student | 11 | 17% |
| Student > Bachelor | 7 | 11% |
| Other | 6 | 9% |
| Professor | 4 | 6% |
| Other | 10 | 15% |
| Unknown | 13 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 17 | 26% |
| Agricultural and Biological Sciences | 9 | 14% |
| Neuroscience | 5 | 8% |
| Biochemistry, Genetics and Molecular Biology | 4 | 6% |
| Psychology | 3 | 5% |
| Other | 12 | 18% |
| Unknown | 15 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 October 2015.
All research outputs
#12,906,644
of 22,771,140 outputs
Outputs from Current Rheumatology Reports
#403
of 709 outputs
Outputs of similar age
#169,583
of 362,502 outputs
Outputs of similar age from Current Rheumatology Reports
#8
of 10 outputs
Altmetric has tracked 22,771,140 research outputs across all sources so far. This one is in the 42nd percentile – i.e., 42% of other outputs scored the same or lower than it.
So far Altmetric has tracked 709 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.0. This one is in the 42nd percentile – i.e., 42% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 362,502 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 52% of its contemporaries.
We're also able to compare this research output to 10 others from the same source and published within six weeks on either side of this one. This one has scored higher than 2 of them.