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Modular Total Syntheses of the Marine-Derived Resorcylic Acid Lactones Cochliomycins A and B Using a Late-Stage Nozaki–Hiyama–Kishi Macrocyclization Reaction

Overview of attention for article published in Journal of Organic Chemistry, November 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (84th percentile)
  • High Attention Score compared to outputs of the same age and source (88th percentile)

Mentioned by

blogs
1 blog
patent
2 patents

Citations

dimensions_citation
29 Dimensions

Readers on

mendeley
23 Mendeley
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Title
Modular Total Syntheses of the Marine-Derived Resorcylic Acid Lactones Cochliomycins A and B Using a Late-Stage Nozaki–Hiyama–Kishi Macrocyclization Reaction
Published in
Journal of Organic Chemistry, November 2014
DOI 10.1021/jo5024602
Pubmed ID
Authors

Benoit Bolte, Jose A. Basutto, Christopher S. Bryan, Mary J. Garson, Martin G. Banwell, Jas S. Ward

Abstract

The natural products cochliomycin A (1) and cochliomycin B (2), two resorcylic acid lactones obtained from marine sources, have been prepared in a concise and stereocontrolled manner from the readily accessible building blocks 4-6. Olefin cross-metathesis, trans-esterification and Nozaki-Hiyama-Kishi (NHK) macrocyclization reactions were employed in the key steps. Hydrolysis of the immediate precursor to cochliomycin B affords the resorcylic acid lactone zeaenol (24).

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 23 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 23 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 4 17%
Student > Master 4 17%
Student > Doctoral Student 3 13%
Researcher 3 13%
Student > Ph. D. Student 3 13%
Other 5 22%
Unknown 1 4%
Readers by discipline Count As %
Chemistry 16 70%
Chemical Engineering 1 4%
Pharmacology, Toxicology and Pharmaceutical Science 1 4%
Environmental Science 1 4%
Physics and Astronomy 1 4%
Other 1 4%
Unknown 2 9%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 April 2020.
All research outputs
#4,368,252
of 25,377,790 outputs
Outputs from Journal of Organic Chemistry
#3,484
of 28,613 outputs
Outputs of similar age
#57,665
of 369,750 outputs
Outputs of similar age from Journal of Organic Chemistry
#15
of 136 outputs
Altmetric has tracked 25,377,790 research outputs across all sources so far. Compared to these this one has done well and is in the 82nd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 28,613 research outputs from this source. They receive a mean Attention Score of 4.5. This one has done well, scoring higher than 87% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 369,750 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 84% of its contemporaries.
We're also able to compare this research output to 136 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 88% of its contemporaries.