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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Free radicals and senescence
|
|---|---|
| Published in |
Experimental Cell Research, January 2008
|
| DOI | 10.1016/j.yexcr.2008.01.011 |
| Pubmed ID | |
| Authors |
Teng Lu, Toren Finkel |
| Abstract |
There is a significant body of experimental evidence that a rise in intracellular reactive oxygen species (ROS) contributes to senescence. Here we review experiments where entry into senescence has been evaluated in cells whose intracellular ROS levels have been modulated by growth in either high or low ambient oxygen concentrations, or where the cellular antioxidant status has been perturbed. In addition, we discuss the observations that senescence triggered by oncogene expression also appears to be in part mediated by a rise in ROS levels. Finally, we discuss the emerging evidence that in vivo senescence might also be triggered by a rise in cellular oxidant levels. Although these data tend to support a role for ROS in mediating senescence, significant questions remain as to whether ROS act in a random or specific fashion and what precise oxidant species acts as the potential senescence trigger. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 159 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 1% |
| United States | 2 | 1% |
| Spain | 2 | 1% |
| Canada | 2 | 1% |
| Brazil | 1 | <1% |
| India | 1 | <1% |
| Australia | 1 | <1% |
| France | 1 | <1% |
| China | 1 | <1% |
| Other | 0 | 0% |
| Unknown | 146 | 92% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 28 | 18% |
| Student > Master | 24 | 15% |
| Researcher | 21 | 13% |
| Student > Bachelor | 20 | 13% |
| Professor | 9 | 6% |
| Other | 34 | 21% |
| Unknown | 23 | 14% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 54 | 34% |
| Biochemistry, Genetics and Molecular Biology | 41 | 26% |
| Medicine and Dentistry | 14 | 9% |
| Pharmacology, Toxicology and Pharmaceutical Science | 4 | 3% |
| Psychology | 3 | 2% |
| Other | 15 | 9% |
| Unknown | 28 | 18% |
Attention Score in Context
This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 January 2019.
All research outputs
#5,339,559
of 25,374,917 outputs
Outputs from Experimental Cell Research
#491
of 5,318 outputs
Outputs of similar age
#24,359
of 170,072 outputs
Outputs of similar age from Experimental Cell Research
#5
of 27 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done well and is in the 78th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 5,318 research outputs from this source. They receive a mean Attention Score of 4.1. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 170,072 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 85% of its contemporaries.
We're also able to compare this research output to 27 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 81% of its contemporaries.