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Increased levels of IL-6 in the cerebrospinal fluid of patients with chronic schizophrenia — significance for activation of the kynurenine pathway

Overview of attention for article published in Journal of Psychiatry & Neuroscience : JPN, March 2015
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (82nd percentile)
  • High Attention Score compared to outputs of the same age and source (88th percentile)

Mentioned by

blogs
1 blog
twitter
2 X users
googleplus
1 Google+ user

Citations

dimensions_citation
181 Dimensions

Readers on

mendeley
177 Mendeley
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Title
Increased levels of IL-6 in the cerebrospinal fluid of patients with chronic schizophrenia — significance for activation of the kynurenine pathway
Published in
Journal of Psychiatry & Neuroscience : JPN, March 2015
DOI 10.1503/jpn.140126
Pubmed ID
Authors

Lilly Schwieler, Markus K Larsson, Elisabeth Skogh, Magdalena E Kegel, Funda Orhan, Sally Abdelmoaty, Anja Finn, Maria Bhat, Martin Samuelsson, Kristina Lundberg, Marja-Liisa Dahl, Carl Sellgren, Ina Schuppe-Koistinen, Camilla Svensson, Sophie Erhardt, Göran Engberg

Abstract

Accumulating evidence indicates that schizophrenia is associated with brain immune activation. While a number of reports suggest increased cytokine levels in patients with schizophrenia, many of these studies have been limited by their focus on peripheral cytokines or confounded by various antipsychotic treatments. Here, well-characterized patients with schizophrenia, all receiving olanzapine treatment, and healthy volunteers were analyzed with regard to cerebrospinal fluid (CSF) levels of cytokines. We correlated the CSF cytokine levels to previously analyzed metabolites of the kynurenine (KYN) pathway.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 177 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Netherlands 1 <1%
Canada 1 <1%
Australia 1 <1%
Brazil 1 <1%
Unknown 173 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 34 19%
Student > Master 23 13%
Student > Bachelor 22 12%
Researcher 16 9%
Other 10 6%
Other 29 16%
Unknown 43 24%
Readers by discipline Count As %
Medicine and Dentistry 38 21%
Agricultural and Biological Sciences 23 13%
Neuroscience 22 12%
Biochemistry, Genetics and Molecular Biology 10 6%
Psychology 10 6%
Other 19 11%
Unknown 55 31%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 August 2015.
All research outputs
#4,148,177
of 25,654,806 outputs
Outputs from Journal of Psychiatry & Neuroscience : JPN
#185
of 807 outputs
Outputs of similar age
#47,748
of 271,650 outputs
Outputs of similar age from Journal of Psychiatry & Neuroscience : JPN
#1
of 9 outputs
Altmetric has tracked 25,654,806 research outputs across all sources so far. Compared to these this one has done well and is in the 83rd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 807 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 14.7. This one has done well, scoring higher than 77% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 271,650 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 82% of its contemporaries.
We're also able to compare this research output to 9 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them