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Antitubercular and Cytotoxic Chlorinated seco-Cyclohexenes from Uvaria alba

Overview of attention for article published in Journal of Natural Products, November 2017
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (83rd percentile)
  • High Attention Score compared to outputs of the same age and source (94th percentile)

Mentioned by

blogs
1 blog
twitter
4 X users

Citations

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18 Dimensions

Readers on

mendeley
33 Mendeley
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Title
Antitubercular and Cytotoxic Chlorinated seco-Cyclohexenes from Uvaria alba
Published in
Journal of Natural Products, November 2017
DOI 10.1021/acs.jnatprod.7b00679
Pubmed ID
Authors

Allan Patrick G. Macabeo, Arianne G. Letada, Simon Budde, Christian Faderl, Hans-Martin Dahse, Scott G. Franzblau, Grecebio Jonathan D. Alejandro, Gregory K. Pierens, Mary J. Garson

Abstract

Two new chlorine-containing polyoxygenated seco-cyclohexenes, albanols A (1) and B (2), along with the oxepinone metabolite grandiuvarone (3) were isolated from the endemic Philippine Annonaceae plant Uvaria alba. Both new compounds exhibited modest antitubercular activity. Compound 1 showed cytostatic activity (ranging from 1-50 μM) against HeLa cells and weak antiproliferative activity against HUVEC and K-562 cells with GI50 values of 106 and 81 μM, respectively.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 33 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 33 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 6 18%
Student > Master 4 12%
Student > Bachelor 4 12%
Lecturer 2 6%
Student > Doctoral Student 2 6%
Other 5 15%
Unknown 10 30%
Readers by discipline Count As %
Chemistry 14 42%
Agricultural and Biological Sciences 4 12%
Medicine and Dentistry 2 6%
Unspecified 1 3%
Biochemistry, Genetics and Molecular Biology 1 3%
Other 0 0%
Unknown 11 33%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 June 2022.
All research outputs
#3,610,137
of 25,085,910 outputs
Outputs from Journal of Natural Products
#435
of 5,238 outputs
Outputs of similar age
#74,680
of 450,685 outputs
Outputs of similar age from Journal of Natural Products
#5
of 69 outputs
Altmetric has tracked 25,085,910 research outputs across all sources so far. Compared to these this one has done well and is in the 85th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 5,238 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.1. This one has done particularly well, scoring higher than 91% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 450,685 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 83% of its contemporaries.
We're also able to compare this research output to 69 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 94% of its contemporaries.