Chapter title |
The many faces of prolactin in breast cancer.
|
---|---|
Chapter number | 3 |
Book title |
Recent Advances in Prolactin Research
|
Published in |
Advances in experimental medicine and biology, January 2015
|
DOI | 10.1007/978-3-319-12114-7_3 |
Pubmed ID | |
Book ISBNs |
978-3-31-912113-0, 978-3-31-912114-7
|
Authors |
Wen Y Chen, Chen, Wen Y |
Abstract |
Prolactin (PRL) is a neuroendocrine polypeptide hormone primarily produced by the lactotrophs in the anterior pituitary gland of all vertebrates. The physiological role of PRL in mammary glands is relatively certain while its role in breast tumor has been a topic of debate for over 20 years. In this review, the author attempts to briefly summarize the data coming from his laboratory in the past years, focusing on G129R, a PRL receptor (PRLR) antagonist developed by introducing a single amino acid substitution mutation into human PRL (hPRL) at position 129, and a variety of G129R derivatives. The author has proposed two novel ideas for potential use of PRL, not anti-PRL agents, as an adjuvant agent for breast cancer, making it a hormone of many faces. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Belgium | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 1 | 7% |
Unknown | 13 | 93% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 4 | 29% |
Student > Bachelor | 2 | 14% |
Librarian | 1 | 7% |
Researcher | 1 | 7% |
Professor > Associate Professor | 1 | 7% |
Other | 0 | 0% |
Unknown | 5 | 36% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 3 | 21% |
Biochemistry, Genetics and Molecular Biology | 2 | 14% |
Arts and Humanities | 2 | 14% |
Nursing and Health Professions | 2 | 14% |
Agricultural and Biological Sciences | 1 | 7% |
Other | 0 | 0% |
Unknown | 4 | 29% |