Title |
Genome-Wide Meta-Analyses of Plasma Renin Activity and Concentration Reveal Association With the Kininogen 1 and Prekallikrein Genes
|
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Published in |
Circulation: Genomic and Precision Medicine, December 2014
|
DOI | 10.1161/circgenetics.114.000613 |
Pubmed ID | |
Authors |
Wolfgang Lieb, Ming-Huei Chen, Alexander Teumer, Rudolf A de Boer, Honghuang Lin, Ervin R Fox, Solomon K Musani, James G Wilson, Thomas J Wang, Henry Völzke, Ann-Kristin Petersen, Christine Meisinger, Matthias Nauck, Sabrina Schlesinger, Yong Li, Jöel Menard, Serge Hercberg, H-Erich Wichmann, Uwe Völker, Rajesh Rawal, Martin Bidlingmaier, Anke Hannemann, Marcus Dörr, Rainer Rettig, Wiek H van Gilst, Dirk J van Veldhuisen, Stephan J L Bakker, Gerjan Navis, Henri Wallaschofski, Pierre Meneton, Pim van der Harst, Martin Reincke, Ramachandran S Vasan |
Abstract |
-The renin-angiotensin-aldosterone-system (RAAS) is critical for regulation of blood pressure and fluid balance and influences cardiovascular remodeling. Dysregulation of the RAAS contributes to cardiovascular and renal morbidity. The genetic architecture of circulating RAAS components is incompletely understood. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 2 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Qatar | 1 | 2% |
Brazil | 1 | 2% |
Unknown | 40 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 9 | 21% |
Professor | 7 | 17% |
Researcher | 5 | 12% |
Student > Ph. D. Student | 5 | 12% |
Professor > Associate Professor | 3 | 7% |
Other | 5 | 12% |
Unknown | 8 | 19% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 13 | 31% |
Biochemistry, Genetics and Molecular Biology | 7 | 17% |
Agricultural and Biological Sciences | 7 | 17% |
Computer Science | 2 | 5% |
Sports and Recreations | 1 | 2% |
Other | 1 | 2% |
Unknown | 11 | 26% |