Title |
Atypical Manifestation of LRBA Deficiency with Predominant IBD-like Phenotype
|
---|---|
Published in |
Inflammatory Bowel Diseases, January 2015
|
DOI | 10.1097/mib.0000000000000266 |
Pubmed ID | |
Authors |
Nina Kathrin Serwas, Aydan Kansu, Elisangela Santos-Valente, Zarife Kuloğlu, Arzu Demir, Aytaç Yaman, Laura Yaneth Gamez Diaz, Reha Artan, Ersin Sayar, Arzu Ensari, Bodo Grimbacher, Kaan Boztug |
Abstract |
Inflammatory bowel diseases (IBDs) denote a heterogeneous group of disorders associated with an imbalance of gut microbiome and the immune system. Importance of the immune system in the gut is endorsed by the presence of IBD-like symptoms in several primary immunodeficiencies. A fraction of early-onset IBDs presenting with more severe disease course and incomplete response to conventional treatment is assumed to be inherited in a Mendelian fashion, as exemplified by the recent discovery of interleukin (IL)-10 (receptor) deficiency. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Austria | 1 | 33% |
United States | 1 | 33% |
Unknown | 1 | 33% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 3 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Hong Kong | 1 | <1% |
Spain | 1 | <1% |
Unknown | 108 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 18 | 16% |
Student > Ph. D. Student | 15 | 14% |
Student > Master | 14 | 13% |
Student > Bachelor | 11 | 10% |
Student > Doctoral Student | 7 | 6% |
Other | 16 | 15% |
Unknown | 29 | 26% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 33 | 30% |
Agricultural and Biological Sciences | 15 | 14% |
Biochemistry, Genetics and Molecular Biology | 12 | 11% |
Immunology and Microbiology | 8 | 7% |
Psychology | 3 | 3% |
Other | 6 | 5% |
Unknown | 33 | 30% |