| Title |
Invariant Natural Killer T Cells are Reduced in Hereditary Hemochromatosis Patients
|
|---|---|
| Published in |
Journal of Clinical Immunology, December 2014
|
| DOI | 10.1007/s10875-014-0118-0 |
| Pubmed ID | |
| Authors |
M. L. Maia, C. S. Pereira, G. Melo, I. Pinheiro, M. A. Exley, G. Porto, M. F. Macedo |
| Abstract |
Invariant natural killer T (iNKT) cells are CD1d restricted-T cells that react to lipid antigens. iNKT cells were shown to be important in infection, autoimmunity and tumor surveillance. Alterations in the number and function of these cells were described in several pathological conditions including autoimmune and/or liver diseases. CD1d is critical for antigen presentation to iNKT cells, and its expression is increased in liver diseases. The liver is the major organ affected in Hereditary Hemochromatosis (HH), an autosomal recessive disorder caused by excessive iron absorption. Herein, we describe the study of iNKT cells of HH patients. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 28 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Portugal | 1 | 4% |
| Unknown | 27 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 7 | 25% |
| Student > Master | 5 | 18% |
| Researcher | 3 | 11% |
| Student > Bachelor | 2 | 7% |
| Lecturer > Senior Lecturer | 1 | 4% |
| Other | 3 | 11% |
| Unknown | 7 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 5 | 18% |
| Medicine and Dentistry | 5 | 18% |
| Immunology and Microbiology | 5 | 18% |
| Biochemistry, Genetics and Molecular Biology | 3 | 11% |
| Veterinary Science and Veterinary Medicine | 1 | 4% |
| Other | 2 | 7% |
| Unknown | 7 | 25% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 February 2015.
All research outputs
#18,385,510
of 22,772,779 outputs
Outputs from Journal of Clinical Immunology
#1,125
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#260,623
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Outputs of similar age from Journal of Clinical Immunology
#11
of 19 outputs
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