Title |
Pioglitazone and bladder cancer risk: a multipopulation pooled, cumulative exposure analysis
|
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Published in |
Diabetologia, December 2014
|
DOI | 10.1007/s00125-014-3456-9 |
Pubmed ID | |
Authors |
Daniel Levin, Samira Bell, Reijo Sund, Sirpa A. Hartikainen, Jaakko Tuomilehto, Eero Pukkala, Ilmo Keskimäki, Ellena Badrick, Andrew G. Renehan, Iain E. Buchan, Samantha L. Bowker, Jasjeet K. Minhas-Sandhu, Zafar Zafari, Carlo Marra, Jeffrey A. Johnson, Bruno H. Stricker, Andrè G. Uitterlinden, Albert Hofman, Rikje Ruiter, Catherine E. de Keyser, Thomas M. MacDonald, Sarah H. Wild, Paul M. McKeigue, Helen M. Colhoun, on behalf of the Scottish Diabetes Research Network Epidemiology Group and the Diabetes and Cancer Research Consortium |
Abstract |
The evidence on the association between pioglitazone use and bladder cancer is contradictory, with many studies subject to allocation bias. The aim of our study was to examine the effect of exposure to pioglitazone on bladder cancer risk internationally across several cohorts. The potential for allocation bias was minimised by focusing on the cumulative effect of pioglitazone as the primary endpoint using a time-dependent approach. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 6 | 25% |
United Kingdom | 5 | 21% |
United States | 2 | 8% |
New Zealand | 1 | 4% |
Argentina | 1 | 4% |
Unknown | 9 | 38% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 16 | 67% |
Practitioners (doctors, other healthcare professionals) | 4 | 17% |
Scientists | 3 | 13% |
Science communicators (journalists, bloggers, editors) | 1 | 4% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 2 | 2% |
Finland | 1 | <1% |
Unknown | 112 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 18 | 16% |
Student > Master | 15 | 13% |
Student > Ph. D. Student | 14 | 12% |
Other | 12 | 10% |
Student > Doctoral Student | 8 | 7% |
Other | 25 | 22% |
Unknown | 23 | 20% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 38 | 33% |
Pharmacology, Toxicology and Pharmaceutical Science | 15 | 13% |
Biochemistry, Genetics and Molecular Biology | 10 | 9% |
Neuroscience | 3 | 3% |
Nursing and Health Professions | 3 | 3% |
Other | 15 | 13% |
Unknown | 31 | 27% |