Title |
A case of acute kidney injury caused by granulomatous interstitial nephritis associated with sarcoidosis
|
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Published in |
CEN Case Reports, November 2017
|
DOI | 10.1007/s13730-017-0287-9 |
Pubmed ID | |
Authors |
Taro Horino, Tatsuki Matsumoto, Kosuke Inoue, Osamu Ichii, Yoshio Terada |
Abstract |
Sarcoidosis affects multiple organs including lung, heart and kidney. Sarcoidosis causes hypercalcemia, hypergammaglobulinemia, and rarely, granulomatous interstitial nephritis, resulting in renal stromal damage. Granulomatous interstitial nephritis is characterized as interstitial nephritis with noncaseating epithelioid granulomas. Diagnosing granulomatous interstitial nephritis before patient's death is challenging; hence, only few cases proven by renal biopsy have been reported till date. We present a case of acute kidney injury caused by granulomatous interstitial nephritis as a renal manifestation of sarcoidosis proven by renal biopsy, which can be confirmed by 18F-fluorodeoxyglucose positron emission tomography/computed tomography. Glucocorticoid therapy was helpful for improving and maintaining her renal function over a 6-year period. |
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Geographical breakdown
Country | Count | As % |
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United States | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 14 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 3 | 21% |
Student > Master | 2 | 14% |
Lecturer | 1 | 7% |
Professor | 1 | 7% |
Student > Doctoral Student | 1 | 7% |
Other | 2 | 14% |
Unknown | 4 | 29% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 6 | 43% |
Biochemistry, Genetics and Molecular Biology | 1 | 7% |
Decision Sciences | 1 | 7% |
Nursing and Health Professions | 1 | 7% |
Unknown | 5 | 36% |