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Insertion sequence transpositions and point mutations in mgrB causing colistin resistance in a clinical strain of carbapenem-resistant Klebsiella pneumoniae from Vietnam

Overview of attention for article published in International Journal of Antimicrobial Agents, November 2017
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (85th percentile)
  • High Attention Score compared to outputs of the same age and source (83rd percentile)

Mentioned by

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1 news outlet
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4 X users

Citations

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29 Dimensions

Readers on

mendeley
54 Mendeley
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Title
Insertion sequence transpositions and point mutations in mgrB causing colistin resistance in a clinical strain of carbapenem-resistant Klebsiella pneumoniae from Vietnam
Published in
International Journal of Antimicrobial Agents, November 2017
DOI 10.1016/j.ijantimicag.2017.11.012
Pubmed ID
Authors

Björn Berglund, Ngoc Thi Bich Hoang, Maria Tärnberg, Ngai Kien Le, Olov Svartström, Dung Thi Khanh Khu, Maud Nilsson, Hai Thanh Le, Jenny Welander, Linus Olson, Mattias Larsson, Lennart E. Nilsson, Håkan Hanberger

Abstract

Resistance among Klebsiella pneumoniae to the last resort antibiotics carbapenems and colistin is increasing worldwide. In this study, we used whole-genome sequencing to determine the colistin resistance mechanisms in clinical isolates of carbapenem- and colistin-resistant K. pneumoniae from Vietnam. Alterations in the regulatory gene mgrB, via mutations and insertion sequence transpositions, was found in 30 of 31 isolates, emphasizing the importance of this resistance mechanism in colistin-resistant K. pneumoniae.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 54 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 54 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 13 24%
Student > Bachelor 7 13%
Student > Master 6 11%
Student > Ph. D. Student 4 7%
Professor 2 4%
Other 4 7%
Unknown 18 33%
Readers by discipline Count As %
Immunology and Microbiology 14 26%
Medicine and Dentistry 8 15%
Biochemistry, Genetics and Molecular Biology 3 6%
Pharmacology, Toxicology and Pharmaceutical Science 2 4%
Veterinary Science and Veterinary Medicine 2 4%
Other 6 11%
Unknown 19 35%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 February 2019.
All research outputs
#3,114,789
of 25,382,440 outputs
Outputs from International Journal of Antimicrobial Agents
#410
of 3,031 outputs
Outputs of similar age
#64,937
of 446,214 outputs
Outputs of similar age from International Journal of Antimicrobial Agents
#9
of 54 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. Compared to these this one has done well and is in the 87th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,031 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 22.3. This one has done well, scoring higher than 86% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 446,214 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 85% of its contemporaries.
We're also able to compare this research output to 54 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 83% of its contemporaries.