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Nonsense Mutations in the Shelterin Complex Genes ACD and TERF2IP in Familial Melanoma

Overview of attention for article published in JNCI: Journal of the National Cancer Institute, December 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (88th percentile)
  • Good Attention Score compared to outputs of the same age and source (69th percentile)

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20 X users
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1 Facebook page

Citations

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144 Dimensions

Readers on

mendeley
129 Mendeley
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2 CiteULike
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Title
Nonsense Mutations in the Shelterin Complex Genes ACD and TERF2IP in Familial Melanoma
Published in
JNCI: Journal of the National Cancer Institute, December 2014
DOI 10.1093/jnci/dju408
Pubmed ID
Authors

Lauren G Aoude, Antonia L Pritchard, Carla Daniela Robles-Espinoza, Karin Wadt, Mark Harland, Jiyeon Choi, Michael Gartside, Víctor Quesada, Peter Johansson, Jane M Palmer, Andrew J Ramsay, Xijun Zhang, Kristine Jones, Judith Symmons, Elizabeth A Holland, Helen Schmid, Vanessa Bonazzi, Susan Woods, Ken Dutton-Regester, Mitchell S Stark, Helen Snowden, Remco van Doorn, Grant W Montgomery, Nicholas G Martin, Thomas M Keane, Carlos López-Otín, Anne-Marie Gerdes, Håkan Olsson, Christian Ingvar, Ake Borg, Nelleke A Gruis, Jeffrey M Trent, Göran Jönsson, D Timothy Bishop, Graham J Mann, Julia A Newton-Bishop, Kevin M Brown, David J Adams, Nicholas K Hayward

Abstract

The shelterin complex protects chromosomal ends by regulating how the telomerase complex interacts with telomeres. Following the recent finding in familial melanoma of inactivating germline mutations in POT1, encoding a member of the shelterin complex, we searched for mutations in the other five components of the shelterin complex in melanoma families.

X Demographics

X Demographics

The data shown below were collected from the profiles of 20 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 129 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 129 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 27 21%
Researcher 25 19%
Student > Doctoral Student 11 9%
Student > Bachelor 10 8%
Student > Master 7 5%
Other 21 16%
Unknown 28 22%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 38 29%
Agricultural and Biological Sciences 26 20%
Medicine and Dentistry 23 18%
Computer Science 2 2%
Pharmacology, Toxicology and Pharmaceutical Science 2 2%
Other 8 6%
Unknown 30 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 July 2015.
All research outputs
#3,254,079
of 25,374,917 outputs
Outputs from JNCI: Journal of the National Cancer Institute
#2,056
of 7,844 outputs
Outputs of similar age
#42,947
of 361,007 outputs
Outputs of similar age from JNCI: Journal of the National Cancer Institute
#33
of 107 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done well and is in the 87th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 7,844 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 21.2. This one has gotten more attention than average, scoring higher than 73% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 361,007 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 107 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.