| Title |
Does microbiota composition affect thyroid homeostasis?
|
|---|---|
| Published in |
Endocrine, December 2014
|
| DOI | 10.1007/s12020-014-0509-2 |
| Pubmed ID | |
| Authors |
Camilla Virili, Marco Centanni |
| Abstract |
The intestinal microbiota is essential for the host to ensure digestive and immunologic homeostasis. When microbiota homeostasis is impaired and dysbiosis occurs, the malfunction of epithelial barrier leads to intestinal and systemic disorders, chiefly immunologic and metabolic. The role of the intestinal tract is crucial in the metabolism of nutrients, drugs, and hormones, including exogenous and endogenous iodothyronines as well as micronutrients involved in thyroid homeostasis. However, the link between thyroid homeostasis and microbiota composition is not yet completely ascertained. A pathogenetic link with dysbiosis has been described in different autoimmune disorders but not yet fully elucidated in autoimmune thyroid disease which represents the most frequent of them. Anyway, it has been suggested that intestinal dysbiosis may trigger autoimmune thyroiditis. Furthermore, hypo- and hyper-thyroidism, often of autoimmune origin, were respectively associated to small intestinal bacterial overgrowth and to changes in microbiota composition. Whether some steps of this thyroid network may be affected by intestinal microbiota composition is briefly discussed below. |
X Demographics
The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Italy | 1 | 20% |
| Unknown | 4 | 80% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 5 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 146 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | <1% |
| Unknown | 145 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 29 | 20% |
| Student > Master | 22 | 15% |
| Researcher | 18 | 12% |
| Student > Ph. D. Student | 11 | 8% |
| Student > Doctoral Student | 8 | 5% |
| Other | 27 | 18% |
| Unknown | 31 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 32 | 22% |
| Nursing and Health Professions | 23 | 16% |
| Agricultural and Biological Sciences | 18 | 12% |
| Biochemistry, Genetics and Molecular Biology | 17 | 12% |
| Immunology and Microbiology | 12 | 8% |
| Other | 11 | 8% |
| Unknown | 33 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 19. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 March 2023.
All research outputs
#1,942,395
of 25,420,980 outputs
Outputs from Endocrine
#94
of 1,930 outputs
Outputs of similar age
#24,670
of 347,787 outputs
Outputs of similar age from Endocrine
#3
of 32 outputs
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