Title |
Protection from diabetes-induced atherosclerosis and renal disease by d-carnosine-octylester: effects of early vs late inhibition of advanced glycation end-products in Apoe-null mice
|
---|---|
Published in |
Diabetologia, December 2014
|
DOI | 10.1007/s00125-014-3467-6 |
Pubmed ID | |
Authors |
Stefano Menini, Carla Iacobini, Carlo Ricci, Claudia Blasetti Fantauzzi, Giuseppe Pugliese |
Abstract |
AGEs are involved in diabetic complications and might be responsible for the phenomenon of 'hyperglycaemic memory'. D-Carnosine-octylester (DCO) has been shown to attenuate AGE formation and vascular and renal injury induced by high-fat diet in Apoe-null mice. This study aimed to verify the protective effect of DCO in atherosclerosis and renal disease induced by experimental diabetes and to discover whether reduction of AGE formation by early vs late DCO treatment provides better macro and microvascular protection. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
Japan | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Science communicators (journalists, bloggers, editors) | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 39 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 39 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 8 | 21% |
Student > Ph. D. Student | 6 | 15% |
Researcher | 4 | 10% |
Student > Bachelor | 3 | 8% |
Student > Postgraduate | 3 | 8% |
Other | 8 | 21% |
Unknown | 7 | 18% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 9 | 23% |
Agricultural and Biological Sciences | 7 | 18% |
Sports and Recreations | 4 | 10% |
Biochemistry, Genetics and Molecular Biology | 3 | 8% |
Nursing and Health Professions | 1 | 3% |
Other | 4 | 10% |
Unknown | 11 | 28% |
Attention Score in Context
This research output has an Altmetric Attention Score of 54. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 January 2023.
All research outputs
#684,067
of 23,267,128 outputs
Outputs from Diabetologia
#366
of 5,115 outputs
Outputs of similar age
#9,249
of 363,433 outputs
Outputs of similar age from Diabetologia
#7
of 42 outputs
Altmetric has tracked 23,267,128 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 5,115 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 22.9. This one has done particularly well, scoring higher than 92% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 363,433 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 42 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 85% of its contemporaries.