Title |
Mismatch Negativity and P3a in Adolescents and Young Adults with Autism Spectrum Disorders: Behavioral Correlates and Clinical Implications
|
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Published in |
Journal of Autism and Developmental Disorders, December 2017
|
DOI | 10.1007/s10803-017-3426-4 |
Pubmed ID | |
Authors |
Yi-Ling Chien, Ming Hsien Hsieh, Susan Shur-Fen Gau |
Abstract |
In a sample of 37 adolescents and young adults with autism spectrum disorder (ASD) and 35 typically-developing controls (TDC), we investigated sensory symptoms by clinical measures, and Mismatch Negativity and P3a component at Fz with the frequency and duration oddball paradigms of event-related potentials. Results showed that compared to TDC, ASD participants reported more sensory symptoms, and presented a shorter P3a peak latency in the duration paradigm, which was correlated with more social awareness deficits. In the frequency paradigm, P3a parameters were correlated with sensation avoiding and attention characteristics of ASD. Our findings suggest that sensory abnormality in ASD may extend into adolescence and young adulthood. P3a latency might be a potential neurophysiological marker for ASD. |
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Geographical breakdown
Country | Count | As % |
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United Kingdom | 1 | 33% |
Canada | 1 | 33% |
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Demographic breakdown
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Members of the public | 2 | 67% |
Scientists | 1 | 33% |
Mendeley readers
Geographical breakdown
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Unknown | 86 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 15 | 17% |
Student > Ph. D. Student | 12 | 14% |
Student > Bachelor | 8 | 9% |
Researcher | 7 | 8% |
Student > Doctoral Student | 6 | 7% |
Other | 10 | 12% |
Unknown | 28 | 33% |
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Psychology | 20 | 23% |
Neuroscience | 10 | 12% |
Nursing and Health Professions | 4 | 5% |
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Medicine and Dentistry | 4 | 5% |
Other | 6 | 7% |
Unknown | 38 | 44% |