Title |
The histone chaperone HJURP is a new independent prognostic marker for luminal A breast carcinoma
|
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Published in |
Molecular Oncology, November 2014
|
DOI | 10.1016/j.molonc.2014.11.002 |
Pubmed ID | |
Authors |
Rocío Montes de Oca, Zachary A. Gurard-Levin, Frédérique Berger, Haniya Rehman, Elise Martel, Armelle Corpet, Leanne de Koning, Isabelle Vassias, Laurence O.W. Wilson, Didier Meseure, Fabien Reyal, Alexia Savignoni, Bernard Asselain, Xavier Sastre-Garau, Geneviève Almouzni |
Abstract |
Breast cancer is a heterogeneous disease with different molecular subtypes that have varying responses to therapy. An ongoing challenge in breast cancer research is to distinguish high-risk patients from good prognosis patients. This is particularly difficult in the low-grade, ER-positive luminal A tumors, where robust diagnostic tools to aid clinical treatment decisions are lacking. Recent data implicating chromatin regulators in cancer initiation and progression offers a promising avenue to develop new tools to help guide clinical decisions. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
France | 2 | 50% |
Unknown | 2 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 3 | 75% |
Scientists | 1 | 25% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 2% |
Unknown | 62 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 13 | 21% |
Student > Ph. D. Student | 11 | 17% |
Student > Master | 8 | 13% |
Student > Bachelor | 7 | 11% |
Student > Doctoral Student | 4 | 6% |
Other | 7 | 11% |
Unknown | 13 | 21% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 18 | 29% |
Agricultural and Biological Sciences | 11 | 17% |
Medicine and Dentistry | 9 | 14% |
Pharmacology, Toxicology and Pharmaceutical Science | 3 | 5% |
Nursing and Health Professions | 2 | 3% |
Other | 5 | 8% |
Unknown | 15 | 24% |