Title |
Assessment of Spirometry and Impulse Oscillometry in Relation to Asthma Control
|
---|---|
Published in |
Lung, December 2014
|
DOI | 10.1007/s00408-014-9674-6 |
Pubmed ID | |
Authors |
Arvind Manoharan, William J. Anderson, Joseph Lipworth, Brian J. Lipworth |
Abstract |
Guidelines advocate the use of spirometry to assess pulmonary function in asthmatic patients. Commonly used measures include forced expiratory volume in 1 s (FEV1), forced expiratory ratio (FEV1/FVC), and forced mid-expiratory flow between 25 and 75 % of forced vital capacity (FEF25-75). Impulse oscillometry (IOS) is an effort-independent test performed during tidal breathing. IOS may be used to assess the total and central airway resistance at 5 Hz (R5) and 20 Hz (R20), respectively, and hence derive the peripheral airway resistance from the difference (R5-R20). We compared spirometry and IOS as tests of global airway function (i.e., FEV1, FEV1/FVC, R5) and putative measures of small airways function (i.e., FEF25-75, R5-R20) and their relationship to oral steroid and short-acting beta-agonist (SABA) use as surrogates for long-term asthma control. |
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Mendeley readers
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