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Genetic variation in PBMC-produced IFN-γ and TNF-α associations with relapse in multiple sclerosis

Overview of attention for article published in Journal of the Neurological Sciences, December 2014
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Title
Genetic variation in PBMC-produced IFN-γ and TNF-α associations with relapse in multiple sclerosis
Published in
Journal of the Neurological Sciences, December 2014
DOI 10.1016/j.jns.2014.12.022
Pubmed ID
Authors

Yuan Zhou, Bruce Taylor, Ingrid van der Mei, Niall Stewart, Jac Charlesworth, Leigh Blizzard, Anne-Louise Ponsonby, Terence Dwyer, Fotini Pittas, Steve Simpson

Abstract

Alterations in peripheral blood mononuclear cell (PBMC) cytokine production have been found in multiple sclerosis (MS) compared to healthy controls. We have previously found that stimulated PBMC-produced TNF-α and IFN-γ modulated MS relapse risk, such that raised TNF-α was protective, while raised IFN-γ increased relapse risk.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 59 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Chile 1 2%
Unknown 58 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 13 22%
Student > Ph. D. Student 12 20%
Student > Bachelor 9 15%
Student > Master 7 12%
Other 4 7%
Other 7 12%
Unknown 7 12%
Readers by discipline Count As %
Medicine and Dentistry 19 32%
Agricultural and Biological Sciences 17 29%
Immunology and Microbiology 4 7%
Biochemistry, Genetics and Molecular Biology 4 7%
Psychology 2 3%
Other 3 5%
Unknown 10 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 December 2014.
All research outputs
#16,720,137
of 25,371,288 outputs
Outputs from Journal of the Neurological Sciences
#3,475
of 5,250 outputs
Outputs of similar age
#210,600
of 360,158 outputs
Outputs of similar age from Journal of the Neurological Sciences
#47
of 87 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 5,250 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.3. This one is in the 29th percentile – i.e., 29% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 360,158 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 38th percentile – i.e., 38% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 87 others from the same source and published within six weeks on either side of this one. This one is in the 29th percentile – i.e., 29% of its contemporaries scored the same or lower than it.