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Biobetters

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Cover of 'Biobetters'

Table of Contents

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    Book Overview
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    Chapter 1 Targeting Glucocerebrosidase to Macrophages for Effective Treatment of Patients with Gaucher Disease: Setting the Paradigm of a “Fit for Purpose” Approach to Enzyme Replacement Therapy
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    Chapter 2 Challenges of Enzyme Replacement Therapy: Poor Tissue Distribution in Lysosomal Diseases Using Pompe Disease as a Model
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    Chapter 3 Muscle Targeting
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    Chapter 4 Blood–Brain Barrier Targeting of Therapeutic Lysosomal Enzymes
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    Chapter 5 Novel Methods for Addressing Immunogenicity of Therapeutic Enzymes
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    Chapter 6 Structure of Monoclonal Antibodies
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    Chapter 7 Prediction of Aggregation In Vivo by Studies of Therapeutic Proteins in Human Plasma
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    Chapter 8 Effect of Hydrolytic Degradation on the In Vivo Properties of Monoclonal Antibodies
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    Chapter 9 Oxidation of Proteins in the In Vivo Environment: What We Know; What We Need to Study and Potential Mitigation Strategies
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    Chapter 10 Molecular Assessment of Monoclonal Antibody-Based Therapeutics Enabling Lead Selection for Clinical Development
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    Chapter 11 Perspectives on Engineering Biobetter Therapeutic Proteins with Greater Stability in Inflammatory Environments
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    Chapter 12 Antibody-Like Molecules Designed for Superior Targeting and Pharmacokinetics
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    Chapter 13 Alternative Protein Scaffolds as Novel Biotherapeutics
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    Chapter 14 Current Strategies for Pharmacokinetic Optimization
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    Chapter 15 Biosimilar and Biobetter Scenarios for the US and Europe: What Should We Expect?
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    Chapter 16 Building Biobetters: The Regulatory Landscape
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Citations

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Readers on

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28 Mendeley
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Title
Biobetters
Published by
Springer-Verlag New York, January 2015
DOI 10.1007/978-1-4939-2543-8
ISBNs
978-1-4939-2543-8, 978-1-4939-2542-1, 978-1-4939-4994-6
Editors

Amy Rosenberg, Barthélemy Demeule

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 28 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 28 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 5 18%
Student > Master 5 18%
Researcher 4 14%
Student > Bachelor 3 11%
Student > Doctoral Student 1 4%
Other 1 4%
Unknown 9 32%
Readers by discipline Count As %
Chemistry 5 18%
Pharmacology, Toxicology and Pharmaceutical Science 3 11%
Biochemistry, Genetics and Molecular Biology 3 11%
Agricultural and Biological Sciences 3 11%
Economics, Econometrics and Finance 2 7%
Other 4 14%
Unknown 8 29%