Title |
Heritability and genome-wide analyses of problematic peer relationships during childhood and adolescence
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Published in |
Human Genetics, December 2014
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DOI | 10.1007/s00439-014-1514-5 |
Pubmed ID | |
Authors |
Beate St Pourcain, C. M. A. Haworth, O. S. P. Davis, Kai Wang, Nicholas J. Timpson, David M. Evans, John P. Kemp, Angelica Ronald, Tom Price, Emma Meaburn, Susan M. Ring, Jean Golding, Hakon Hakonarson, R. Plomin, George Davey Smith |
Abstract |
Peer behaviour plays an important role in the development of social adjustment, though little is known about its genetic architecture. We conducted a twin study combined with a genome-wide complex trait analysis (GCTA) and a genome-wide screen to characterise genetic influences on problematic peer behaviour during childhood and adolescence. This included a series of longitudinal measures (parent-reported Strengths-and-Difficulties Questionnaire) from a UK population-based birth-cohort (ALSPAC, 4-17 years), and a UK twin sample (TEDS, 4-11 years). Longitudinal twin analysis (TEDS; N ≤ 7,366 twin pairs) showed that peer problems in childhood are heritable (4-11 years, 0.60 < twin-h (2) ≤ 0.71) but genetically heterogeneous from age to age (4-11 years, twin-r g = 0.30). |
X Demographics
Geographical breakdown
Country | Count | As % |
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United Kingdom | 2 | 22% |
Spain | 1 | 11% |
Unknown | 6 | 67% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 6 | 67% |
Science communicators (journalists, bloggers, editors) | 1 | 11% |
Practitioners (doctors, other healthcare professionals) | 1 | 11% |
Scientists | 1 | 11% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 88 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 13 | 15% |
Student > Ph. D. Student | 12 | 14% |
Researcher | 10 | 11% |
Student > Bachelor | 6 | 7% |
Professor | 4 | 5% |
Other | 13 | 15% |
Unknown | 30 | 34% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 14 | 16% |
Psychology | 11 | 13% |
Biochemistry, Genetics and Molecular Biology | 6 | 7% |
Social Sciences | 6 | 7% |
Agricultural and Biological Sciences | 5 | 6% |
Other | 13 | 15% |
Unknown | 33 | 38% |