Title |
Vasopressors for acute myocardial infarction complicated by cardiogenic shock
|
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Published in |
Medizinische Klinik - Intensivmedizin und Notfallmedizin, December 2017
|
DOI | 10.1007/s00063-017-0378-6 |
Pubmed ID | |
Authors |
R. Prondzinsky, K. Hirsch, L. Wachsmuth, M. Buerke, S. Unverzagt |
Abstract |
Several international evidence-based guidelines reveal the lack of evidence on the treatment of patients with acute myocardial infarction (AMI) complicated by cardiogenic shock (CS) for all recommended therapies. We included 6 studies with 842 eligible patients and one ongoing study. Three different adrenergic agents (norepinephrine, dopamine, epinephrine), vasopressin and the NOS inhibitor tilarginine were compared in 4 different combinations. On the small basis of all available evidence we can state that there is no evidence to use tilarginene, some evidence to avoid dopamine due to increased rates of arrhythmias, but some evidence, which suggests to prefer norepinephrine in comparison to epinephrine as vasopressor. |
X Demographics
Geographical breakdown
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 20 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Doctoral Student | 3 | 15% |
Student > Bachelor | 2 | 10% |
Student > Postgraduate | 2 | 10% |
Student > Ph. D. Student | 2 | 10% |
Other | 1 | 5% |
Other | 3 | 15% |
Unknown | 7 | 35% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 8 | 40% |
Nursing and Health Professions | 3 | 15% |
Computer Science | 1 | 5% |
Biochemistry, Genetics and Molecular Biology | 1 | 5% |
Unknown | 7 | 35% |