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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Nucleosome positioning is unaltered at MLH1 splice site mutations in cells derived from Lynch syndrome patients
|
|---|---|
| Published in |
Clinical Epigenetics, December 2014
|
| DOI | 10.1186/s13148-014-0032-6 |
| Pubmed ID | |
| Authors |
Mathew A Sloane, Luke B Hesson, Andrea C Nunez, Bryony A Thompson, Robyn L Ward |
| Abstract |
Splicing is more efficient when coupled with transcription and it has been proposed that nucleosomes enriched in exons are important for splice site recognition. Lynch syndrome is a familial cancer syndrome that can be caused by the autosomal dominant inheritance of splice site mutations in the MutL homolog 1 (MLH1) gene. To better understand the role of nucleosomes in splicing, we used MLH1 splice site mutations in Lynch syndrome cases as a model to investigate if abnormal splicing was associated with altered nucleosome positioning at exon-intron boundaries. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 12 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 12 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 6 | 50% |
| Student > Ph. D. Student | 3 | 25% |
| Other | 1 | 8% |
| Student > Doctoral Student | 1 | 8% |
| Unknown | 1 | 8% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 5 | 42% |
| Medicine and Dentistry | 3 | 25% |
| Agricultural and Biological Sciences | 1 | 8% |
| Decision Sciences | 1 | 8% |
| Computer Science | 1 | 8% |
| Other | 0 | 0% |
| Unknown | 1 | 8% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 January 2015.
All research outputs
#15,313,289
of 22,775,504 outputs
Outputs from Clinical Epigenetics
#849
of 1,245 outputs
Outputs of similar age
#209,642
of 354,732 outputs
Outputs of similar age from Clinical Epigenetics
#18
of 21 outputs
Altmetric has tracked 22,775,504 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,245 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.5. This one is in the 25th percentile – i.e., 25% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 354,732 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 31st percentile – i.e., 31% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 21 others from the same source and published within six weeks on either side of this one. This one is in the 4th percentile – i.e., 4% of its contemporaries scored the same or lower than it.