Title |
The Use of Vancomycin Powder In Modern Spine Surgery: Systematic Review and Meta-Analysis of the Clinical Evidence
|
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Published in |
World Neurosurgery, December 2014
|
DOI | 10.1016/j.wneu.2014.12.033 |
Pubmed ID | |
Authors |
Joshua Bakhsheshian, Nader S. Dahdaleh, Sandi K. Lam, Jason W. Savage, Zachary A. Smith |
Abstract |
Surgical Site Infections (SSIs) can lead to higher postoperative morbidity, mortality, and health care costs. Despite current prophylactic measures, SSIs rates have been reported in up to 15% of patients undergoing spine surgery. Adjunctive local application of vancomycin powder in spine surgery is a low-cost strategy to help reduce SSIs. Vancomycin is active against skin pathogens that can potentially contaminate the wound during spinal surgery. The local application of vancomycin in its powder form ensures adequate surgical site concentrations while minimizing adverse effects due to undetectable systemic distribution. However, clinical studies have produced conflicting results and the clinical evidence behind the use of vancomycin powder in modern spinal surgery practices is not clear. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Venezuela, Bolivarian Republic of | 1 | 17% |
United States | 1 | 17% |
Spain | 1 | 17% |
United Kingdom | 1 | 17% |
Germany | 1 | 17% |
Unknown | 1 | 17% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 4 | 67% |
Practitioners (doctors, other healthcare professionals) | 2 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 1% |
Spain | 1 | <1% |
Japan | 1 | <1% |
Unknown | 191 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 38 | 19% |
Other | 29 | 15% |
Student > Bachelor | 17 | 9% |
Student > Postgraduate | 15 | 8% |
Student > Doctoral Student | 12 | 6% |
Other | 43 | 22% |
Unknown | 41 | 21% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 94 | 48% |
Pharmacology, Toxicology and Pharmaceutical Science | 10 | 5% |
Neuroscience | 8 | 4% |
Nursing and Health Professions | 6 | 3% |
Biochemistry, Genetics and Molecular Biology | 3 | 2% |
Other | 20 | 10% |
Unknown | 54 | 28% |