| Title |
What We Know About Diet, Genes, and Dyslipidemia: Is There Potential for Translation?
|
|---|---|
| Published in |
Current Nutrition Reports, October 2013
|
| DOI | 10.1007/s13668-013-0065-z |
| Pubmed ID | |
| Authors |
Toni I. Pollin, Michael Quartuccio |
| Abstract |
Cardiovascular disease, particularly coronary artery disease (CAD), is the leading cause of death in the United States. Dyslipidemia, including elevated low density lipoprotein cholesterol (LDL-C) and triglyceride (TG) levels and low high density lipoprotein cholesterol (HDL-C), is a well-established risk factor for CAD and is influenced by both genetic and lifestyle factors, including the diet and dietary fat in particular. Major strides in elucidating the genetic basis for dyslipidemia have been made in recent years, and the quest to clarify how genetic differences influence lipid response to dietary intervention continues. Some monogenic conditions such as famililal hypercholesterolemia and sitosterolemia already have customized dietary recommendations. Some promising associations have emerged for more polygenic dyslipidemia, but further studies are needed in large dietary intervention studies capturing increasing amounts of explainable genetic variation before recommendations can be made for clinical translation. |
Mendeley readers
The data shown below were compiled from readership statistics for 45 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 45 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 7 | 16% |
| Student > Master | 6 | 13% |
| Student > Bachelor | 6 | 13% |
| Student > Doctoral Student | 4 | 9% |
| Student > Ph. D. Student | 4 | 9% |
| Other | 11 | 24% |
| Unknown | 7 | 16% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 12 | 27% |
| Biochemistry, Genetics and Molecular Biology | 3 | 7% |
| Agricultural and Biological Sciences | 3 | 7% |
| Nursing and Health Professions | 2 | 4% |
| Immunology and Microbiology | 2 | 4% |
| Other | 6 | 13% |
| Unknown | 17 | 38% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 December 2014.
All research outputs
#20,247,117
of 22,775,504 outputs
Outputs from Current Nutrition Reports
#293
of 325 outputs
Outputs of similar age
#184,132
of 210,866 outputs
Outputs of similar age from Current Nutrition Reports
#8
of 9 outputs
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So far Altmetric has tracked 325 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 17.4. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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