| Title |
Dietary Fructose and Hypertension
|
|---|---|
| Published in |
Current Hypertension Reports, October 2010
|
| DOI | 10.1007/s11906-010-0163-x |
| Pubmed ID | |
| Authors |
Magdalena Madero, Santos E. Perez-Pozo, Diana Jalal, Richard J. Johnson, Laura G. Sánchez-Lozada |
| Abstract |
The association between fructose and increased blood pressure is still incompletely defined, because experimental studies have produced dissimilar conclusions. Amplified vasopressor responses to minimal stimuli and differing responses to fructose in peripheral versus central sites may explain the controversy. Fructose induces systemic hypertension through several mechanisms mainly associated with deleterious effects on target organs (kidney, endothelium, heart) exerted by the byproducts of its metabolism, such as uric acid. The kidney is particularly sensitive to the effects of fructose because high loads of this sugar reach renal tissue. In addition, fructose increases reabsorption of salt and water in the small intestine and kidney; thus the combination of salt and fructose has a synergistic effect in the development of hypertension. Clinical and epidemiologic studies have also linked fructose consumption with hypertension. Further studies are warranted in order to understand the role of fructose in the development of hypertension. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 101 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 2% |
| Indonesia | 1 | <1% |
| Australia | 1 | <1% |
| France | 1 | <1% |
| Canada | 1 | <1% |
| Croatia | 1 | <1% |
| Unknown | 94 | 93% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 15 | 15% |
| Student > Bachelor | 13 | 13% |
| Student > Master | 12 | 12% |
| Other | 9 | 9% |
| Student > Ph. D. Student | 8 | 8% |
| Other | 24 | 24% |
| Unknown | 20 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 33 | 33% |
| Agricultural and Biological Sciences | 20 | 20% |
| Biochemistry, Genetics and Molecular Biology | 11 | 11% |
| Pharmacology, Toxicology and Pharmaceutical Science | 5 | 5% |
| Nursing and Health Professions | 2 | 2% |
| Other | 9 | 9% |
| Unknown | 21 | 21% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 December 2014.
All research outputs
#15,313,289
of 22,775,504 outputs
Outputs from Current Hypertension Reports
#458
of 732 outputs
Outputs of similar age
#79,505
of 99,278 outputs
Outputs of similar age from Current Hypertension Reports
#9
of 10 outputs
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