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Mendeley readers
Attention Score in Context
| Title |
Improved surgical margin definition by narrow band imaging for resection of oral squamous cell carcinoma: A prospective gene expression profiling study
|
|---|---|
| Published in |
Head & Neck, June 2015
|
| DOI | 10.1002/hed.23989 |
| Pubmed ID | |
| Authors |
Camile S Farah, Andrew J Dalley, Phan Nguyen, Martin Batstone, Farzaneh Kordbacheh, Joanna Perry-Keene, David Fielding |
| Abstract |
Background: Incomplete primary tumour excision contributes to localised post-surgical recurrence of oral squamous cell carcinoma (OSCC). The objective was to provide molecular evidence that surgical margin definition using Narrow Band Imaging (NBI) resulted in more complete OSCC excision than conventional white light (WL) panendoscopy. Methods: Molecular divergence between tumour, WL and NBI defined surgical margins was compared in 18 patients through microarray analysis (GeneChip®U133-plus-2.0). Results: The numbers of differentially expressed genes (NBI: 4387; WL: 3266; versus tumour) signified that NBI placed margins into less involved tissue than WL examination. Principal Component Analysis segregated tumour, WL and NBI tissues appropriately based solely on mRNA profiles, and unsupervised hierarchical clustering identified four patients (22%) who benefited directly from NBI surgical margin definition. Gene ontology enrichment indicated increasing cell phenotypic diversity: Tumour<WL<NBI. Conclusions: Resection to NBI defined margins will leave less dysplastic and malignant residual tissue and thereby increase ablative surgery success rates. This article is protected by copyright. All rights reserved. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| India | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 38 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 38 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 5 | 13% |
| Researcher | 5 | 13% |
| Professor | 4 | 11% |
| Student > Master | 4 | 11% |
| Student > Bachelor | 3 | 8% |
| Other | 8 | 21% |
| Unknown | 9 | 24% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 16 | 42% |
| Agricultural and Biological Sciences | 1 | 3% |
| Nursing and Health Professions | 1 | 3% |
| Psychology | 1 | 3% |
| Engineering | 1 | 3% |
| Other | 0 | 0% |
| Unknown | 18 | 47% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 December 2014.
All research outputs
#19,990,545
of 24,565,648 outputs
Outputs from Head & Neck
#2,605
of 3,888 outputs
Outputs of similar age
#195,485
of 268,495 outputs
Outputs of similar age from Head & Neck
#72
of 176 outputs
Altmetric has tracked 24,565,648 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,888 research outputs from this source. They receive a mean Attention Score of 2.7. This one is in the 18th percentile – i.e., 18% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 268,495 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 15th percentile – i.e., 15% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 176 others from the same source and published within six weeks on either side of this one. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.