| Title |
Synergy of leptin/STAT3 with HER2 receptor induces tamoxifen resistance in breast cancer cells through regulation of apoptosis-related genes
|
|---|---|
| Published in |
Cellular Oncology, December 2014
|
| DOI | 10.1007/s13402-014-0213-5 |
| Pubmed ID | |
| Authors |
Vassilis Papanikolaou, Nikolaos Stefanou, Stephanie Dubos, Ioanna Papathanasiou, Maria Palianopoulou, Vaia Valiakou, Aspasia Tsezou |
| Abstract |
Tamoxifen is a major treatment modality for estrogen receptor positive breast cancer, but the occurrence of resistance remains a problem. Recently, obesity-related leptin has been found to interfere with tamoxifen in breast cancer MCF-7 cells. In the present study we investigated the effect of leptin on three tamoxifen-treated breast cancer cell types (i.e., MDA-MB-231, MCF-7 and MCF-7/HER2). |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| France | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 33 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Mexico | 1 | 3% |
| United States | 1 | 3% |
| Unknown | 31 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 5 | 15% |
| Professor | 5 | 15% |
| Student > Master | 4 | 12% |
| Student > Bachelor | 3 | 9% |
| Researcher | 3 | 9% |
| Other | 7 | 21% |
| Unknown | 6 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 9 | 27% |
| Agricultural and Biological Sciences | 7 | 21% |
| Medicine and Dentistry | 4 | 12% |
| Chemistry | 2 | 6% |
| Pharmacology, Toxicology and Pharmaceutical Science | 1 | 3% |
| Other | 2 | 6% |
| Unknown | 8 | 24% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 December 2014.
All research outputs
#21,498,958
of 23,999,200 outputs
Outputs from Cellular Oncology
#316
of 426 outputs
Outputs of similar age
#305,875
of 360,271 outputs
Outputs of similar age from Cellular Oncology
#4
of 7 outputs
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So far Altmetric has tracked 426 research outputs from this source. They receive a mean Attention Score of 2.7. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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