| Title |
Flexible micro(bio)sensors for quantitative analysis of bioanalytes in a nanovolume of human lachrymal liquid
|
|---|---|
| Published in |
Analytical & Bioanalytical Chemistry, February 2013
|
| DOI | 10.1007/s00216-013-6756-x |
| Pubmed ID | |
| Authors |
Viktor Andoralov, Sergey Shleev, Thomas Arnebrant, Tautgirdas Ruzgas |
| Abstract |
A flexible electrochemical micro(bio)sensor has been designed for determination of several biological compounds, specifically, ascorbate, dopamine, and glucose, in human lachrymal liquid (tears). The microsensor for simultaneous determination of ascorbate and dopamine concentrations was based on a gold microwire modified with the tetrathiafulvalen-7,7,8,8-tetracyanoquinodimethane complex as a catalyst. To monitor glucose concentration in tears, glucose dehydrogenase was immobilized on a gold microwire modified with carbon nanotubes and an osmium redox polymer. A capillary microcell was constructed for sampling tears. The cell had a working volume of 60-100 nL with a sampling deviation of 6.7%. To check if the microcell was properly filled with buffer or tear sample, a control electrode was introduced into the construction. The electrode was used to measure the electrical resistance of a fully filled nanovolume cell. The mechanical flexibility is one of the most important features of the prototype and allowed direct collection of tears with minimized risk of damage to the eye. |
Mendeley readers
The data shown below were compiled from readership statistics for 49 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Sweden | 1 | 2% |
| Denmark | 1 | 2% |
| Poland | 1 | 2% |
| Unknown | 46 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 10 | 20% |
| Researcher | 7 | 14% |
| Student > Ph. D. Student | 7 | 14% |
| Professor > Associate Professor | 5 | 10% |
| Student > Bachelor | 4 | 8% |
| Other | 8 | 16% |
| Unknown | 8 | 16% |
| Readers by discipline | Count | As % |
|---|---|---|
| Chemistry | 16 | 33% |
| Engineering | 10 | 20% |
| Agricultural and Biological Sciences | 3 | 6% |
| Medicine and Dentistry | 3 | 6% |
| Materials Science | 3 | 6% |
| Other | 3 | 6% |
| Unknown | 11 | 22% |
Attention Score in Context
This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 January 2015.
All research outputs
#6,741,089
of 25,374,647 outputs
Outputs from Analytical & Bioanalytical Chemistry
#1,520
of 9,619 outputs
Outputs of similar age
#66,737
of 292,398 outputs
Outputs of similar age from Analytical & Bioanalytical Chemistry
#22
of 89 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one has received more attention than most of these and is in the 73rd percentile.
So far Altmetric has tracked 9,619 research outputs from this source. They receive a mean Attention Score of 3.1. This one has done well, scoring higher than 84% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 292,398 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 77% of its contemporaries.
We're also able to compare this research output to 89 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 75% of its contemporaries.