Title |
Adipose tissue derived stem cells: in vitro and in vivo analysis of a standard and three commercially available cell-assisted lipotransfer techniques
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Published in |
Stem Cell Research & Therapy, January 2015
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DOI | 10.1186/scrt536 |
Pubmed ID | |
Authors |
Rossana Domenis, Lara Lazzaro, Sarah Calabrese, Damiano Mangoni, Annarita Gallelli, Evgenia Bourkoula, Ivana Manini, Natascha Bergamin, Barbara Toffoletto, Carlo A Beltrami, Antonio P Beltrami, Daniela Cesselli, Pier Camillo Parodi |
Abstract |
Autologous fat grafting is commonly used to correct soft-tissue contour deformities. However, results are impaired by a variable and unpredictable resorption rate. Autologous adipose-derived stromal cells in combination with lipoinjection (cell-assisted lipotransfer) seem to favor a long-term persistence of fat grafts, thus fostering the development of devices to be used in the operating room at the point of care, to isolate the stromal vascular fraction (SVF) and produce SVF-enhanced fat grafts with safe and standardized protocols. Focusing on patients undergoing breast reconstruction by lipostructure, we analyzed a standard technique, a modification of the Coleman's procedure, and three different commercially available devices (Lipokit, Cytori, Fastem), in terms of 1) ability to enrich fat grafts in stem cells and 2) clinical outcome at 6 and 12 months. |
X Demographics
Geographical breakdown
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Unknown | 2 | 100% |
Demographic breakdown
Type | Count | As % |
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Scientists | 1 | 50% |
Mendeley readers
Geographical breakdown
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Spain | 2 | 1% |
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Italy | 1 | <1% |
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Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 21 | 14% |
Other | 15 | 10% |
Student > Master | 15 | 10% |
Student > Bachelor | 10 | 7% |
Other | 30 | 20% |
Unknown | 35 | 24% |
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Immunology and Microbiology | 2 | 1% |
Other | 15 | 10% |
Unknown | 42 | 28% |